CEP63 and ROGDI

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CEP63	ROGDI
Description		centrosomal protein 63	rogdi atypical leucine zipper
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GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Centriolar Satellite Ciliary Basal Body	Nucleus Nuclear Envelope Synaptic Vesicle Axon Dendrite Cytoplasmic Vesicle Cell Projection Perikaryon RAVE Complex Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynapse
	Molecular Function	Protein Binding Molecular Adaptor Activity	Protein Binding
	Biological Process	DNA Damage Checkpoint Signaling DNA Damage Response Centriole Replication Proteasomal Protein Catabolic Process Signal Transduction In Response To DNA Damage Innate Immune Response Negative Regulation Of Innate Immune Response Protein Stabilization Spindle Assembly Cell Division De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Negative Regulation Of Protein K63-linked Ubiquitination	Regulation Of PH Brain Development Memory Locomotory Behavior Positive Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Gene Expression Neurogenesis Hemopoiesis Bone Mineralization Locomotion Odontogenesis Of Dentin-containing Tooth Locomotor Rhythm PH Reduction Circadian Behavior Nervous System Process Neuromuscular Process Enamel Mineralization Amelogenesis
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Height ( 18391952) Hip circumference adjusted for BMI ( 34021172) Late-onset Alzheimer's disease ( 27770636) Neurocognitive impairment in HIV-1 infection (dichotomous) ( 28447399) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500)	Night sleep phenotypes ( 27126917)
Interacting Genes		66 interacting genes: ALOX5 ARFIP2 ARNT2 BFSP2 BRPF1 CAMKK2 CAPN7 CCDC14 CCDC187 CCHCR1 CCNI CDK1 CEP57 CEP57L1 CWF19L2 DAXX DISC1 DSCAM DST DTNB DZIP3 EXOC4 EZH2 FAM161A FBF1 FEM1C GSE1 HAUS1 HGS INTS6L KANK2 KXD1 MACF1 MBIP MNS1 NCOR2 NDC80 NDEL1 NXT2 PCNX4 PIBF1 POLR3C PPP1R13B PPP4R1 RCOR3 ROGDI SMARCE1 SMC3 SNRNP70 SPTAN1 SPTBN1 SSX3 SYNE1 SYT17 TBC1D15 TBC1D22B TSG101 TSGA10IP TSHZ3 TXLNA USHBP1 USP2 ZCCHC10 ZNF148 ZNF250 ZNF774	4 interacting genes: CEP126 CEP63 COPS6 DISC1
Entrez ID		80254	79641
HPRD ID		07826	13388
Ensembl ID		ENSG00000182923	ENSG00000067836
Uniprot IDs		A0A804HIX3 A0A804HKK0 A0A804HKR1 A0A804HL17 H0YAL1 Q96MT8	Q9GZN7
PDB IDs		6CSU 6CSV 7W91	5XQH 5XQI
Enriched GO Terms of Interacting Partners?		Centrosome Cytoskeleton Cytoskeleton Organization Microtubule Cytoskeleton Organization Microtubule Binding Microtubule Cytoskeleton Organization Involved In Mitosis Spindle Assembly Microtubule-based Process Nuclear Matrix Protein Binding Organelle Organization Cilium Organization Protein Localization To Centrosome Radial Glia-guided Pyramidal Neuron Migration Polymeric Cytoskeletal Fiber Cyclin Binding Cohesin Complex Establishment Of Mitotic Sister Chromatid Cohesion Mitotic Cohesin Complex Microtubule Intermediate Filament Cytoskeleton Organization Positive Regulation Of Developmental Growth Chromosome, Centromeric Region Positive Regulation Of Axon Extension Organelle Assembly Establishment Of Sister Chromatid Cohesion Spindle Organization Mitotic Spindle Pole Intermediate Filament-based Process Spectrin Mitotic Spindle Organization Mitotic Spindle Assembly Membrane Fission Negative Regulation Of Actin Filament Polymerization Protein Localization To Cytoskeleton Locomotor Rhythm	Non-motile Cilium Assembly Microtubule Cytoskeleton Organization Ciliary Base Centrosome Organelle Assembly Microtubule-based Process Pyramidal Neuron Migration To Cerebral Cortex Cytoskeleton Organization Molecular Adaptor Activity Central Region Of Growth Cone Spindle Organization Regulation Of Post-translational Protein Modification Radial Glia-guided Pyramidal Neuron Migration Cilium Assembly Negative Regulation Of Protein K63-linked Ubiquitination De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation De Novo Centriole Assembly Cilium Organization Cerebral Cortex Radial Glia-guided Migration Negative Regulation Of Protein Polyubiquitination Ciliary Basal Body Protein Deneddylation Regulation Of Protein Metabolic Process Cell Projection Assembly Cytoskeleton Plasma Membrane Bounded Cell Projection Assembly Metal-dependent Deubiquitinase Activity Regulation Of Protein K63-linked Ubiquitination Cell Proliferation In Forebrain Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Cerebral Cortex Radially Oriented Cell Migration Regulation Of Protein Neddylation Protein Neddylation Detection Of Temperature Stimulus Involved In Sensory Perception Mitochondrial Calcium Ion Homeostasis Detection Of Temperature Stimulus Centriole Replication Protein Localization To Centrosome Positive Regulation Of Neuroblast Proliferation Glial Cell Migration Regulation Of Synapse Maturation Cerebral Cortex Cell Migration Regulation Of Protein Polyubiquitination Centriole Assembly Regulation Of Protein Modification Process COP9 Signalosome Dynein Complex Response To Electrical Stimulus Positive Regulation Of Axon Extension Proteolysis Involved In Protein Catabolic Process
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