CEP63 and SSX3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CEP63	SSX3
Gene Name		centrosomal protein 63kDa	synovial sarcoma, X breakpoint 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Centrosome Centriole Cytosol	Nucleus
	Molecular Function	Protein Binding	Nucleic Acid Binding
	Biological Process	DNA Damage Checkpoint G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Centriole Replication Signal Transduction In Response To DNA Damage Spindle Assembly Cell Division	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Height ( 18391952)
Protein-Protein Interactions		44 interactors: ALOX5 ARFIP2 ARNT2 CAMKK2 CCDC14 CCNI CEP57 CEP57L1 DDX26B DISC1 DST DTNB DZIP3 EXOC4 EZH2 FAM161A FBF1 GSE1 HAUS1 KXD1 MACF1 MBIP NCOR2 NDEL1 NXT2 PCNXL4 POLR3C PPP1R13B PPP4R1 SMARCE1 SMC3 SNRNP70 SPTAN1 SPTBN1 SSX3 SYNE1 SYT17 TANK TBC1D15 TSHZ3 TXLNA TXLNB USHBP1 ZCCHC10	15 interactors: AGTRAP CEP63 CEP70 CMTM5 DDIT3 MED4 MEOX2 MIPOL1 PCBD2 RHOJ SSX2IP ZBTB25 ZBTB3 ZNF496 ZSCAN1
Entrez ID		80254	10214
HPRD ID		07826	02265
Ensembl ID		ENSG00000182923	ENSG00000165584
Uniprot IDs		Q96MT8	Q99909
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule Cytoskeleton Organization Organelle Organization Cytoskeleton Organization Microtubule-based Process Cell Cycle Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Cell Cycle Cellular Localization Golgi To Plasma Membrane Protein Transport Cell Cycle Maintenance Of Protein Location In Cell Maintenance Of Protein Location Brain Development Maintenance Of Location In Cell Protein Localization To Organelle Head Development Anatomical Structure Development Golgi To Plasma Membrane Transport Regulation Of Cellular Component Size Positive Regulation Of Axon Extension Intermediate Filament Cytoskeleton Organization Microtubule Anchoring Protein Localization Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Leukotriene Production Involved In Inflammatory Response Kidney Smooth Muscle Cell Differentiation Ureteric Peristalsis Nervous System Development Intermediate Filament-based Process Positive Regulation Of Cell Morphogenesis Involved In Differentiation Protein Localization To Nucleus Regulation Of Cell Cycle Cell Proliferation In Forebrain Actin Filament Capping Central Nervous System Development Mitotic Cell Cycle Process Cellular Protein Localization Cerebral Cortex Radially Oriented Cell Migration Endomembrane System Organization Negative Regulation Of Actin Filament Depolymerization Developmental Process	Negative Regulation Of Myoblast Differentiation Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Myoblast Differentiation Negative Regulation Of Muscle Cell Differentiation Negative Regulation Of Determination Of Dorsal Identity Positive Regulation Of Transcription, DNA-templated Regulation Of Cellular Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription Involved In Anterior/posterior Axis Specification Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Centrosome Organization Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Microtubule Organizing Center Organization G2/M Transition Of Mitotic Cell Cycle Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Vasculature Development Intraciliary Transport Involved In Cilium Morphogenesis Somite Specification Regulation Of Muscle Cell Differentiation Angiotensin-activated Signaling Pathway Tetrahydrobiopterin Biosynthetic Process ER Overload Response Nitrogen Compound Metabolic Process Centriole Replication MRNA Transcription From RNA Polymerase II Promoter Retina Vasculature Morphogenesis In Camera-type Eye Blood Vessel Maturation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress MRNA Transcription Anterior/posterior Pattern Specification Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition
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