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CEP63 and HAUS1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid, proximity labelling technology)
CEP63
HAUS1
Description
centrosomal protein 63
HAUS augmin like complex subunit 1
Image
GO Annotations
Cellular Component
Spindle Pole
Nucleoplasm
Cytoplasm
Centrosome
Centriole
Cytosol
Cytoskeleton
Centriolar Satellite
Ciliary Basal Body
Spindle Pole
Cytoplasm
Centrosome
Spindle
Cytosol
Cytoskeleton
Microtubule
HAUS Complex
Mitotic Spindle Microtubule
Molecular Function
Protein Binding
Molecular Adaptor Activity
Protein Binding
Biological Process
DNA Damage Checkpoint Signaling
DNA Damage Response
Centriole Replication
Proteasomal Protein Catabolic Process
Signal Transduction In Response To DNA Damage
Innate Immune Response
Negative Regulation Of Innate Immune Response
Protein Stabilization
Spindle Assembly
Cell Division
De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation
Negative Regulation Of Protein K63-linked Ubiquitination
Centrosome Cycle
Regulation Of Microtubule Nucleation
Spindle Assembly
Cell Division
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Height (
18391952
)
Hip circumference adjusted for BMI (
34021172
)
Late-onset Alzheimer's disease (
27770636
)
Neurocognitive impairment in HIV-1 infection (dichotomous) (
28447399
)
Waist circumference adjusted for BMI (adjusted for smoking behaviour) (
28443625
)
Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) (
28448500
)
Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) (
28443625
)
Waist circumference adjusted for BMI in active individuals (
28448500
)
Waist circumference adjusted for BMI in non-smokers (
28443625
)
Waist circumference adjusted for body mass index (
25673412
28448500
)
Interacting Genes
66 interacting genes:
ALOX5
ARFIP2
ARNT2
BFSP2
BRPF1
CAMKK2
CAPN7
CCDC14
CCDC187
CCHCR1
CCNI
CDK1
CEP57
CEP57L1
CWF19L2
DAXX
DISC1
DSCAM
DST
DTNB
DZIP3
EXOC4
EZH2
FAM161A
FBF1
FEM1C
GSE1
HAUS1
HGS
INTS6L
KANK2
KXD1
MACF1
MBIP
MNS1
NCOR2
NDC80
NDEL1
NXT2
PCNX4
PIBF1
POLR3C
PPP1R13B
PPP4R1
RCOR3
ROGDI
SMARCE1
SMC3
SNRNP70
SPTAN1
SPTBN1
SSX3
SYNE1
SYT17
TBC1D15
TBC1D22B
TSG101
TSGA10IP
TSHZ3
TXLNA
USHBP1
USP2
ZCCHC10
ZNF148
ZNF250
ZNF774
82 interacting genes:
AK8
ARFIP2
ATP6V1D
BFSP2
BLOC1S6
BORCS6
C3orf62
CAGE1
CBY2
CCDC136
CCDC57
CCHCR1
CDR2
CENPP
CEP170P1
CEP44
CEP55
CEP57L1
CEP63
CEP70
DCTN2
DMD
DTNBP1
FAM161B
FGFR1OP2
GOLGA2
HGS
HOOK2
IFIT3
IFT20
INCA1
KDM1A
KIFC3
KRT1
KRT15
KRT18
KRT19
KRT3
KRT31
KRT38
KRT40
KXD1
LDOC1
LURAP1
MAD1L1
MAGEA6
MCM10
MCM3
MED4
MED7
MIPOL1
MTUS2
NDC80
NECAB2
NINL
NUP54
NUP62
ODAD1
PDE4DIP
PIBF1
PKN1
POLR3C
SPAG5
SSC5D
STX11
SYCE1
SYCE3
TEAD4
TFIP11
TFPT
TRAF1
TRIM23
TRIM27
TRIM54
TRIM69
TSG101
TXN2
USHBP1
VPS37C
VPS52
WASHC3
ZNF471
Entrez ID
80254
115106
HPRD ID
07826
16385
Ensembl ID
ENSG00000182923
ENSG00000152240
Uniprot IDs
A0A804HIX3
A0A804HKK0
A0A804HKR1
A0A804HL17
H0YAL1
Q96MT8
Q96CS2
PDB IDs
6CSU
6CSV
7W91
7SQK
Enriched GO Terms of Interacting Partners
?
Centrosome
Cytoskeleton
Cytoskeleton Organization
Microtubule Cytoskeleton Organization
Microtubule Binding
Microtubule Cytoskeleton Organization Involved In Mitosis
Spindle Assembly
Microtubule-based Process
Nuclear Matrix
Protein Binding
Organelle Organization
Cilium Organization
Protein Localization To Centrosome
Radial Glia-guided Pyramidal Neuron Migration
Polymeric Cytoskeletal Fiber
Cyclin Binding
Cohesin Complex
Establishment Of Mitotic Sister Chromatid Cohesion
Mitotic Cohesin Complex
Microtubule
Intermediate Filament Cytoskeleton Organization
Positive Regulation Of Developmental Growth
Chromosome, Centromeric Region
Positive Regulation Of Axon Extension
Organelle Assembly
Establishment Of Sister Chromatid Cohesion
Spindle Organization
Mitotic Spindle Pole
Intermediate Filament-based Process
Spectrin
Mitotic Spindle Organization
Mitotic Spindle Assembly
Membrane Fission
Negative Regulation Of Actin Filament Polymerization
Protein Localization To Cytoskeleton
Locomotor Rhythm
Cytoskeleton
Organelle Organization
Centrosome
Microtubule-based Process
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Cytoskeleton Organization
Intermediate Filament Organization
Protein Binding
Structural Constituent Of Skin Epidermis
Keratin Filament
Organelle Assembly
Intermediate Filament
Identical Protein Binding
Microtubule Organizing Center Organization
Establishment Of Localization In Cell
Supramolecular Fiber Organization
Organelle Localization
Intracellular Transport
Centrosome Cycle
Microtubule Binding
Intracellular Protein Localization
Protein Localization To Centrosome
Metaphase Chromosome Alignment
Cellular Component Assembly
Protein Transport
Cilium Organization
Centriole Assembly
Spindle Organization
Cellular Localization
Structural Molecule Activity
Establishment Of Protein Localization
Cilium Assembly
Microtubule
Establishment Of Organelle Localization
Chromosome Localization
BLOC-1 Complex
Plasma Membrane Bounded Cell Projection Assembly
Microtubule Cytoskeleton Organization
Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Cell Projection Assembly
Mitotic Metaphase Chromosome Alignment
Protein Localization To Cytoskeleton
Spindle Pole
Structural Constituent Of Cytoskeleton
Vesicle Organization
Centriole
Centriole Replication
Protein Localization To Organelle
Endosomal Transport
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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