CASP1 and PSEN2

  • Number of citations of the paper that reports this interaction (PMID 9219695)
  • 38
  • Data Source:
  • HPRD (in vitro, in vivo)

CASP1

PSEN2

Gene Name caspase 1, apoptosis-related cysteine peptidase presenilin 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 42 interactors: AR ATN1 ATXN3 BCAP31 BCL2L1 BID CARD16 CARD17 CARD8 CASP10 CASP14 CASP4 CASP8 CAST CDK11B EGFR FGF2 HTT IL18 IL1A IL1B IL33 IL37 LMNA MAPT NEDD4 NFE2L2 NLRC4 NLRP1 NOD1 PAK1 PARK2 PARP1 PLA2G4A PLA2G4B PSEN1 PSEN2 PYCARD RIPK2 TFAP2A TIRAP VAC14 58 interactors: AAMP ACTG1 APH1A APH1B APP BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B MGEA5 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1
Entrez ID 834 5664
HPRD ID 00977 02860
Ensembl ID ENSG00000137752 ENSG00000143801
Uniprot IDs A8K249 A8K257 P29466 P49810
PDB IDs 1BMQ 1IBC 1ICE 1RWK 1RWM 1RWN 1RWO 1RWP 1RWV 1RWW 1RWX 1SC1 1SC3 1SC4 2FQQ 2H48 2H4W 2H4Y 2H51 2H54 2HBQ 2HBR 2HBY 2HBZ 3D6F 3D6H 3D6M 3E4C 3NS7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
10ko  acp5  aia  arthritic  arthritis  autoinflammatory  blockade  driven  erosions  ex  exogenous  focal  hence  histological  histopathology  il1b  il33  inflammasome  investigative  joint  neutralization  nlrp3  osteoclast  osteoclastogenesis  pathology  radiographic  synovial  synovium  tartrate 
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
Tagcloud (Difference) ?
10ko  acp5  aia  arthritic  arthritis  autoinflammatory  blockade  driven  erosions  ex  exogenous  focal  hence  histological  histopathology  il1b  il33  inflammasome  investigative  joint  neutralization  nlrp3  osteoclast  osteoclastogenesis  pathology  radiographic  synovial  synovium  tartrate 
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
Tagcloud (Intersection) ?