CASP1 and IL1A

  • Number of citations of the paper that reports this interaction (PMID 18329368)
  • 170
  • Data Source:
  • HPRD (in vivo)

CASP1

IL1A

Gene Name caspase 1, apoptosis-related cysteine peptidase interleukin 1, alpha
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 42 interactors: AR ATN1 ATXN3 BCAP31 BCL2L1 BID CARD16 CARD17 CARD8 CASP10 CASP14 CASP4 CASP8 CAST CDK11B EGFR FGF2 HTT IL18 IL1A IL1B IL33 IL37 LMNA MAPT NEDD4 NFE2L2 NLRC4 NLRP1 NOD1 PAK1 PARK2 PARP1 PLA2G4A PLA2G4B PSEN1 PSEN2 PYCARD RIPK2 TFAP2A TIRAP VAC14 9 interactors: CAPN1 CASP1 HAX1 IL1R1 IL1R2 IL1RAP NDN NFKBIE S100A13
Entrez ID 834 3552
HPRD ID 00977 00988
Ensembl ID ENSG00000137752
Uniprot IDs A8K249 A8K257 P29466 P01583
PDB IDs 1BMQ 1IBC 1ICE 1RWK 1RWM 1RWN 1RWO 1RWP 1RWV 1RWW 1RWX 1SC1 1SC3 1SC4 2FQQ 2H48 2H4W 2H4Y 2H51 2H54 2HBQ 2HBR 2HBY 2HBZ 3D6F 3D6H 3D6M 3E4C 3NS7 1ITA 2ILA 2KKI 2L5X
Enriched GO Terms of Interacting Partners?
Tagcloud ?
10ko  acp5  aia  arthritic  arthritis  autoinflammatory  blockade  driven  erosions  ex  exogenous  focal  hence  histological  histopathology  il1b  il33  inflammasome  investigative  joint  neutralization  nlrp3  osteoclast  osteoclastogenesis  pathology  radiographic  synovial  synovium  tartrate 
45mg  amenable  copy  curative  cytokine  dacomitinib  eligible  endpoint  evaluable  exploratory  forty  goals  harboring  her4  il1b  il4  il6  il8  irreversible  manageable  p16ink4a  pfs  pi3k  pik3ca  platinum  progressed  recistv1  scchn  shorter 
Tagcloud (Difference) ?
10ko  acp5  aia  arthritic  arthritis  autoinflammatory  blockade  driven  erosions  ex  exogenous  focal  hence  histological  histopathology  il33  inflammasome  investigative  joint  neutralization  nlrp3  osteoclast  osteoclastogenesis  pathology  radiographic  synovial  synovium  tartrate 
45mg  amenable  copy  curative  cytokine  dacomitinib  eligible  endpoint  evaluable  exploratory  forty  goals  harboring  her4  il4  il6  il8  irreversible  manageable  p16ink4a  pfs  pi3k  pik3ca  platinum  progressed  recistv1  scchn  shorter 
Tagcloud (Intersection) ?
il1b