CASP1 and PAK1

  • Number of citations of the paper that reports this interaction (PMID 15561713)
  • 25
  • Data Source:
  • HPRD (in vitro, in vivo)

CASP1

PAK1

Gene Name caspase 1, apoptosis-related cysteine peptidase p21 protein (Cdc42/Rac)-activated kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 42 interactors: AR ATN1 ATXN3 BCAP31 BCL2L1 BID CARD16 CARD17 CARD8 CASP10 CASP14 CASP4 CASP8 CAST CDK11B EGFR FGF2 HTT IL18 IL1A IL1B IL33 IL37 LMNA MAPT NEDD4 NFE2L2 NLRC4 NLRP1 NOD1 PAK1 PARK2 PARP1 PLA2G4A PLA2G4B PSEN1 PSEN2 PYCARD RIPK2 TFAP2A TIRAP VAC14 83 interactors: ABI3 ACTA1 ACVR1 AKT1 APP ARHGEF2 ARHGEF6 ARHGEF7 ARPC1B BAD BAIAP2 BMPR1B BMX BRSK1 C5orf42 CASP1 CDC42 CDK11B CDK5 CDK5R1 CHORDC1 COL1A1 CRIPAK CSNK2A1 CSNK2A2 DSCAM DYNLL1 DYNLL2 DYRK1B EGFR ELF3 ERBB2 ESR1 FLNA FOXL2 FOXO1 FRS2 GIT2 GRB2 HGS HIST1H3A HIST1H4A HSP90AA1 LIMK1 MAP2K1 MAP3K1 MAPK1 MBP MYLK MYNN MYO6 NCK1 NCK2 NF2 OXSR1 PAK1IP1 PDPK1 PLCG1 PPM1F PRKCD PXN RAC1 RAF1 RHOJ RHOU SHC1 SMAD1 SMAD2 SMAD4 SMURF1 SORBS2 SORBS3 SYN1 TGFBR1 TGFBR2 TGM2 YWHAG YWHAZ ZBTB18 ZC3H7A ZNF418 ZNF823 ZNF83
Entrez ID 834 5058
HPRD ID 00977 03995
Ensembl ID ENSG00000137752 ENSG00000149269
Uniprot IDs A8K249 A8K257 P29466 B3KNX7 Q13153
PDB IDs 1BMQ 1IBC 1ICE 1RWK 1RWM 1RWN 1RWO 1RWP 1RWV 1RWW 1RWX 1SC1 1SC3 1SC4 2FQQ 2H48 2H4W 2H4Y 2H51 2H54 2HBQ 2HBR 2HBY 2HBZ 3D6F 3D6H 3D6M 3E4C 3NS7 1F3M 1YHV 1YHW 1ZSG 2HY8 2QME 3DVP 3FXZ 3FY0 3Q4Z 3Q52 3Q53 4DAW 4EQC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
10ko  acp5  aia  arthritic  arthritis  autoinflammatory  blockade  driven  erosions  ex  exogenous  focal  hence  histological  histopathology  il1b  il33  inflammasome  investigative  joint  neutralization  nlrp3  osteoclast  osteoclastogenesis  pathology  radiographic  synovial  synovium  tartrate 
advance  belonging  cdc2  cdc42  coordinate  coordinates  coordinating  cot1  delays  dystrophy  encodes  fission  genetically  interphase  maintain  maintains  mitosis  mitotic  morphogenesis  myotonic  orb2  orb6  p34  polarity  polarized  ras1  shape  shk1  threonine 
Tagcloud (Difference) ?
10ko  acp5  aia  arthritic  arthritis  autoinflammatory  blockade  driven  erosions  ex  exogenous  focal  hence  histological  histopathology  il1b  il33  inflammasome  investigative  joint  neutralization  nlrp3  osteoclast  osteoclastogenesis  pathology  radiographic  synovial  synovium  tartrate 
advance  belonging  cdc2  cdc42  coordinate  coordinates  coordinating  cot1  delays  dystrophy  encodes  fission  genetically  interphase  maintain  maintains  mitosis  mitotic  morphogenesis  myotonic  orb2  orb6  p34  polarity  polarized  ras1  shape  shk1  threonine 
Tagcloud (Intersection) ?