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KBTBD7 and NFKBIE
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
KBTBD7
NFKBIE
Gene Name
kelch repeat and BTB (POZ) domain containing 7
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cellular_component
Cytoplasm
Golgi Apparatus
Cytosol
Perinuclear Region Of Cytoplasm
Molecular Function
Molecular_function
Protein Binding
Protein Binding
Biological Process
Biological_process
D-serine Transport
Cytoplasmic Sequestering Of Transcription Factor
Pathways
Signaling by the B Cell Receptor (BCR)
Downstream signaling events of B Cell Receptor (BCR)
Activation of NF-kappaB in B cells
Adaptive Immune System
Drugs
Diseases
GWAS
Rheumatoid arthritis (
22446963
23028356
)
Protein-Protein Interactions
13 interactors:
BARD1
BLMH
C8orf33
CPT1A
DUSP23
GABARAPL1
GABARAPL2
HAP1
LINC00341
LRIF1
MAP1LC3B
NFKBIE
PHC2
15 interactors:
ANKHD1
C1QBP
CUL1
HDAC4
HDAC5
IL1A
JUP
KBTBD7
NCOR2
NFKB1
NFKB2
PPP6C
REL
RELA
SKP1
Entrez ID
84078
4794
HPRD ID
13759
05181
Ensembl ID
ENSG00000146232
Uniprot IDs
Q8WVZ9
O00221
Q96F31
PDB IDs
Enriched GO Terms of Interacting Partners
?
Nucleophagy
Mitochondrion Degradation
Autophagy
Organelle Disassembly
Autophagic Vacuole Assembly
Macroautophagy
Vacuole Organization
Membrane Fusion
Cellular Response To Nitrogen Starvation
Cellular Response To Starvation
Cellular Response To Nutrient Levels
Response To Starvation
Cellular Response To Extracellular Stimulus
Cellular Response To Stress
Positive Regulation Of Neurotrophin Production
Positive Regulation Of Nonmotile Primary Cilium Assembly
Mitochondrion Organization
Catabolic Process
Negative Regulation Of Intracellular Protein Transport
Response To Nutrient Levels
Regulation Of Cellular Localization
Regulation Of Intracellular Transport
D-serine Transport
Negative Regulation Of MRNA 3'-end Processing
Response To Extracellular Stimulus
Organelle Assembly
Negative Regulation Of Intracellular Transport
Regulation Of Organelle Transport Along Microtubule
Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Positive Regulation Of Cilium Assembly
Response To Drug
Regulation Of Protein Transport
Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Protein Polyubiquitination
Negative Regulation Of Protein Export From Nucleus
Regulation Of Establishment Of Protein Localization
Negative Regulation Of Protein Transport
Protein K6-linked Ubiquitination
Positive Regulation Of Fatty Acid Beta-oxidation
Carnitine Shuttle
Regulation Of Nucleocytoplasmic Transport
Hypothalamus Cell Differentiation
Negative Regulation Of Beta-amyloid Formation
Regulation Of Protein Localization
Retrograde Axon Cargo Transport
Carnitine Transmembrane Transport
Carnitine Transport
Membrane Organization
Regulation Of Intracellular Protein Transport
Negative Regulation Of Amyloid Precursor Protein Catabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Inflammatory Response
Negative Regulation Of Transcription From RNA Polymerase II Promoter
NIK/NF-kappaB Signaling
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Interleukin-12 Biosynthetic Process
Regulation Of Interleukin-12 Production
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Defense Response
Negative Regulation Of Biosynthetic Process
Regulation Of Cytokine Production
Regulation Of Cytokine Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Signal Transduction
Positive Regulation Of Cellular Biosynthetic Process
Notch Signaling Pathway
Positive Regulation Of Cytokine Production
Response To Cytokine
Signaling
Response To Organic Substance
Positive Regulation Of Metabolic Process
Cell Communication
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Positive Regulation Of MiRNA Metabolic Process
I-kappaB Kinase/NF-kappaB Signaling
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Cytokine Biosynthetic Process
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Immune System Process
Regulation Of Protein Metabolic Process
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Interleukin-12 Biosynthetic Process
Cellular Response To Nicotine
Cellular Response To Stimulus
Tagcloud
?
1980s
a20
acquire
bearing
budding
ccl17
ccl22
cd23
cd40
cd40l
cd80
chemoattractant
chronically
costimulatory
cytidine
deaminase
humoral
hypergammaglobulinemia
issued
lymphotoxin
map2k1
messengers
nfkb1
productively
tnip1
tonsillar
traf1
virions
Tagcloud (Difference)
?
1980s
a20
acquire
bearing
budding
ccl17
ccl22
cd23
cd40
cd40l
cd80
chemoattractant
chronically
costimulatory
cytidine
deaminase
humoral
hypergammaglobulinemia
issued
lymphotoxin
map2k1
messengers
nfkb1
productively
tnip1
tonsillar
traf1
virions
Tagcloud (Intersection)
?