KBTBD7 and CCDC106

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KBTBD7	CCDC106
Description		kelch repeat and BTB domain containing 7	coiled-coil domain containing 106
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cul3-RING Ubiquitin Ligase Complex	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Protein Binding
	Biological Process	Negative Regulation Of Signal Transduction Protein Ubiquitination Regulation Of Rac Protein Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination
Pathways		Regulation of RAS by GAPs Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes		20 interacting genes: BARD1 BLMH C8orf33 CCDC106 CPT1A DRD2 DUSP23 GABARAP GABARAPL1 GABARAPL2 HAP1 KLF15 LRIF1 MAP1LC3B MAP1LC3C MEOX2 NFKBIE PHC2 PSME3 VANGL2	26 interacting genes: APP ATF4 CACNA1S CEP19 COPS6 CRMP1 EEF1G EIF1AD ERG28 FAM9B KAT5 KBTBD7 L3MBTL2 LRIF1 MAGEA11 MAGOHB NAA10 NKAPD1 NUTF2 PRPF31 RBM48 RCOR3 SDCBP SETDB1 TP53 UTP14A
Entrez ID		84078	29903
HPRD ID		13759	09995
Ensembl ID		ENSG00000120696	ENSG00000173581
Uniprot IDs		Q8WVZ9	K7EMI9 Q9BWC9
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagy Autophagosome Assembly Autophagosome Organization Phospholipid Binding Protein-containing Complex Disassembly GABA Receptor Binding Macroautophagy Vacuole Organization Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Organelle Assembly Response To Nutrient Levels Beta-tubulin Binding Ubiquitin Protein Ligase Binding Catabolic Process Cytoplasmic Vesicle Microtubule Regulation Of Synaptic Transmission, GABAergic Regulation Of Protein Catabolic Process Negative Regulation Of MRNA 3'-end Processing Positive Regulation Of Neurotrophin Production Response To Stress Organelle Membrane Long-chain Fatty Acid Transport	Nucleoplasm Promoter-specific Chromatin Binding Molecular Function Activator Activity Nucleus Cellular Response To Glucose Starvation Cellular Response To Manganese Ion Negative Regulation Of Gene Expression Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Macromolecule Biosynthetic Process Response To Manganese Ion General Transcription Initiation Factor Binding Negative Regulation Of Biosynthetic Process Cytosol Acetyltransferase Activity Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Transcription Regulator Complex
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