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NHP2L1 and POLA2
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
NHP2L1
POLA2
Gene Name
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
polymerase (DNA directed), alpha 2, accessory subunit
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
Nucleolus
Box C/D SnoRNP Complex
Protein Complex
Nucleoplasm
Alpha DNA Polymerase:primase Complex
Cytoplasm
Molecular Function
RNA Binding
Protein Binding
SnoRNA Binding
Poly(A) RNA Binding
Molecular_function
DNA Binding
DNA-directed DNA Polymerase Activity
Protein Heterodimerization Activity
Biological Process
MRNA Splicing, Via Spliceosome
RNA Splicing
Gene Expression
Ribosome Biogenesis
Protein Import Into Nucleus, Translocation
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Telomere Maintenance Via Recombination
Telomere Maintenance
DNA Replication
DNA Replication Initiation
DNA Strand Elongation Involved In DNA Replication
Telomere Maintenance Via Semi-conservative Replication
DNA Biosynthetic Process
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
Activation of the pre-replicative complex
Extension of Telomeres
Activation of the pre-replicative complex
Leading Strand Synthesis
DNA strand elongation
Polymerase switching
DNA replication initiation
Telomere Maintenance
G1/S Transition
Mitotic G1-G1/S phases
E2F mediated regulation of DNA replication
Polymerase switching on the C-strand of the telomere
Telomere C-strand synthesis initiation
Synthesis of DNA
Chromosome Maintenance
Lagging Strand Synthesis
Processive synthesis on the lagging strand
DNA Replication Pre-Initiation
M/G1 Transition
Telomere C-strand (Lagging Strand) Synthesis
S Phase
Cell Cycle, Mitotic
Removal of the Flap Intermediate
Inhibition of replication initiation of damaged DNA by RB1/E2F1
Drugs
Dacarbazine
Diseases
GWAS
Protein-Protein Interactions
14 interactors:
CDKN2C
CHST1
GTF3C1
LRIF1
MAP1LC3B
POLA2
PPIH
PRPF3
PRPF31
PRPF4
RAD17
RBM10
SNW1
XRCC6
31 interactors:
AKTIP
APP
ASCC2
ATP5C1
CPE
CRELD1
DCP2
DDX24
DHX34
EIF6
EZH2
FAM219A
FGFR3
FRZB
HDAC6
HELB
HGH1
IGFBP3
KCNE3
KLF6
LRPAP1
NHP2L1
NR4A1
PARP1
POLA1
PRPF38A
RBM23
SETDB1
STK40
ULK2
XPNPEP1
Entrez ID
4809
23649
HPRD ID
03197
10160
Ensembl ID
ENSG00000100138
Uniprot IDs
P55769
Q6FHM6
Q14181
PDB IDs
1E7K
2JNB
2OZB
3SIU
3SIV
2KEB
4E2I
Enriched GO Terms of Interacting Partners
?
RNA Splicing
MRNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA Metabolic Process
RNA Processing
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Spliceosomal Tri-snRNP Complex Assembly
RNA Metabolic Process
Gene Expression
Cellular Metabolic Process
Spliceosomal SnRNP Assembly
Positive Regulation Of Viral Process
Telomere Maintenance
Positive Regulation Of Vitamin D Receptor Signaling Pathway
Cellular Hyperosmotic Salinity Response
Macromolecule Biosynthetic Process
5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter
TRNA Transcription From RNA Polymerase III Promoter
Cellular Response To X-ray
Regulation Of Vitamin D Receptor Signaling Pathway
Regulation Of Viral Process
G1/S Transition Of Mitotic Cell Cycle
TRNA Transcription
Ribonucleoprotein Complex Assembly
Establishment Of Integrated Proviral Latency
Metabolic Process
Cellular Hyperosmotic Response
Hyperosmotic Salinity Response
Establishment Of Viral Latency
Positive Regulation By Host Of Viral Transcription
Mitotic Cell Cycle Process
DNA Replication Checkpoint
Cellular Response To Salt Stress
DNA Recombination
Mitotic Cell Cycle
DNA Ligation
RNA Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Gene Expression
Developmental Growth
Growth
MRNA Metabolic Process
DNA Replication, Synthesis Of RNA Primer
Regulation Of Growth
Cellular Response To Reactive Oxygen Species
Regulation Of Binding
Regulation Of Receptor Activity
Organ Development
Metabolic Process
RNA Processing
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Cell Development
Positive Regulation Of Programmed Cell Death
Developmental Growth Involved In Morphogenesis
Regulation Of Protein Binding
Positive Regulation Of Cell Death
Histone H3-K9 Modification
Negative Regulation Of Epithelial Cell Differentiation
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Chromosome Organization
Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death
Negative Regulation Of Hepatocyte Differentiation
Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway
Hsp90 Deacetylation
Response To Oxidative Stress
MRNA Processing
RNA Biosynthetic Process
Cochlea Development
Response To Reactive Oxygen Species
Negative Regulation Of Cell Differentiation
Cellular Response To Oxidative Stress
Lung Alveolus Development
Macroautophagy
Regulation Of Cell Differentiation
System Development
Cellular Response To Hydrogen Peroxide
Positive Regulation Of Chaperone-mediated Protein Complex Assembly
Leading Strand Elongation
Synaptic Growth At Neuromuscular Junction
Polyubiquitinated Misfolded Protein Transport
Tagcloud
?
beadchip
ca125
carboplatin
cdkn1b
chek2
ck7
cyfra21
cytokinesis
deserve
exceptional
fancd2
illumina
krt7
lig3
mesothelioma
nt5c
obscure
pemetrexed
phosphorylase
platinum
pold1
prpf19
recq5
sensitize
smrp
sparcl1
transendothelial
ts
tymp
Tagcloud (Difference)
?
beadchip
ca125
carboplatin
cdkn1b
chek2
ck7
cyfra21
cytokinesis
deserve
exceptional
fancd2
illumina
krt7
lig3
mesothelioma
nt5c
obscure
pemetrexed
phosphorylase
platinum
pold1
prpf19
recq5
sensitize
smrp
sparcl1
transendothelial
ts
tymp
Tagcloud (Intersection)
?