BRD3 and MAP1LC3B

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		BRD3	MAP1LC3B
Description		bromodomain containing 3	microtubule associated protein 1 light chain 3 beta
Image
GO Annotations	Cellular Component	Chromatin Nucleus Chromosome	Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Cytosol Cytoskeleton Microtubule Axoneme Endomembrane System Membrane Organelle Membrane Cytoplasmic Vesicle Mitochondrial Membrane
	Molecular Function	Chromatin Binding Protein Serine/threonine Kinase Activity Protein Binding Protein-macromolecule Adaptor Activity Histone Binding Histone H3K9me2/3 Reader Activity LncRNA Binding Histone H3K18cr Reader Activity Histone H3K9cr Reader Activity Histone H3K27cr Reader Activity Histone Reader Activity Molecular Condensate Scaffold Activity	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding Ceramide Binding
	Biological Process	Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Endodermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Protein Localization To Chromatin	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Autophagosome Maturation
Pathways			Macroautophagy PINK1-PRKN Mediated Mitophagy TBC/RABGAPs Receptor Mediated Mitophagy Pexophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex SARS-CoV-2 modulates autophagy KEAP1-NFE2L2 pathway
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 34315874) Alcohol consumption (drinks per week) ( 30643258) Apolipoprotein A1 levels ( 32203549) Aspartate aminotransferase levels ( 34315874) Brain-derived neurotrophic factor levels ( 33345186) Central corneal thickness ( 31798171 29760442) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eosinophil count ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Estimated glomerular filtration rate ( 31152163) Granulocyte percentage of myeloid white cells ( 27863252) HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Intraocular pressure ( 29617998 30591961) Lymphocyte count ( 32888494) Mean platelet volume ( 27863252 32888494) Mosquito bite size ( 28199695) Neutrophil count ( 27863252 32888494) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Platelet count ( 32888494 22139419) Platelet distribution width ( 27863252) Red cell distribution width ( 28957414 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252)	General factor of neuroticism ( 30867560) Major depressive disorder ( 22472876) Metabolite levels ( 23823483) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: APP BRD7 MAP1LC3B MYC SPOP SPP1	97 interacting genes: AAMP ABTB3 ADD1 ADNP AFTPH AMBRA1 ANK2 APPL1 ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BAG6 BIRC6 BNIP3 BRD3 BRD9 CAMSAP1 CARS2 CASP8 CCDC50 CCPG1 CCSER2 CDC37 CLTA CUL3 DBI DBN1 DNMT3B DPPA4 EED EPS8 EVA1A FLCN FUNDC1 GORASP2 HYPK IRGQ KBTBD7 KLHL5 KXD1 LUC7L2 MESD MKRN1 MRFAP1 MRTFA MTX1 MYBL2 NCOR1 NEDD4 NEK9 OPTN PCNT PLEKHM1 PRKCZ PRUNE2 RAD1 RAP1GAP RASAL3 RETREG1 RETREG2 RIC1 RIPOR1 RPLP1 SAMM50 SEM1 SEPTIN3 SMARCB1 SNCA SNU13 SNX18 SPAG9 SQSTM1 STK3 STK36 TAF7 TBC1D17 TBC1D25 TBC1D5 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 TPPP TRIM21 TRIM25 TRIM32 TTN UPF2 USP10 VHL WDR90
Entrez ID		8019	81631
HPRD ID		03327	14358
Ensembl ID		ENSG00000169925	ENSG00000140941
Uniprot IDs		Q15059	Q658J6 Q9GZQ8
PDB IDs		2E7N 2NXB 2OO1 2YW5 3S91 3S92 5A7C 5HFR 5HJC 6BGG 6BGH 6I41 6I5P 6I68 6I7A 6QJU 6U4A 6ULP 7JMY 7JQ8 7JYN 7JYZ 7L72 7L9L 7LAY 7LAZ 7LB4 7LBT 7R8R 7RJK 7RJL 7RJM 7RJN 7S3P 7TO7 7TO8 7TO9 7TOA 7UG5 8B5A 8CV5	1V49 2LUE 2N9X 2ZJD 3VTU 3VTV 3VTW 3WAO 3X0W 4WAA 5D94 5DCN 5GMV 5MS2 5MS5 5MS6 5V4K 5W9A 5XAC 5XAD 5XAE 6J04 6LAN 7ELG 7GA8 7GA9 7GAA 7GAB 7GAC 7GAD 7GAE 7GAF 7GAG 7GAH 7GAI 7GAJ 7GAK 7GAL 7GAM 7GAN 7GAO 7GAP 7GAQ 7GAR 7GAS 7GAU 8Q53 8Q7K 8YV6
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium Epigenetic Regulation Of Gene Expression Regulation Of Response To Calcium Ion Regulation Of MiRNA Transcription Perinuclear Region Of Cytoplasm Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Cellular Response To Stress Striated Muscle Cell Differentiation Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Ubiquitin Protein Ligase Binding Acinar Cell Proliferation Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Memory T Cell Differentiation Regulation Of Cell Cycle Adult Locomotory Behavior Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Regulation Of Cellular Component Organization PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Associative Learning Regulation Of MiRNA Metabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Response To Peptide Response To Cytokine Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Leukocyte Activation Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization NK T Cell Proliferation Myc-Max Complex Muscle Cell Differentiation Regulation Of Acinar Cell Proliferation Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Response To Nutrient Levels TSC1-TSC2 Complex Response To Norepinephrine Integrin Binding Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway	Autophagy Autophagy Of Mitochondrion Mitophagy Macroautophagy Autophagosome Autophagosome Assembly Autophagosome Organization Nucleophagy Organelle Organization Regulation Of Autophagy Vacuole Organization Organelle Assembly Piecemeal Microautophagy Of The Nucleus Protein-phosphatidylethanolamide Deconjugating Activity Microautophagy Catabolic Process Positive Regulation Of Autophagy Protein Delipidation Aggrephagy Cellular Component Assembly Establishment Of Protein Localization Cytoplasm Substrate Localization To Autophagosome Intracellular Protein Localization Protein Transport Protein Binding Positive Regulation Of Catabolic Process Cytosol Endoplasmic Reticulum-autophagosome Adaptor Activity Cellular Localization Establishment Of Localization In Cell Regulation Of Protein Stability Proteolysis Involved In Protein Catabolic Process Cysteine-type Endopeptidase Activity Regulation Of Cellular Component Organization Response To Mitochondrial Depolarisation Proteolysis Regulation Of Organelle Organization Regulation Of Macroautophagy Protein Monoubiquitination GTPase Activator Activity Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Macroautophagy Phagophore Assembly Site Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Catabolic Process Regulation Of Cell Projection Assembly
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