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NUDT18 and TRIM37
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
NUDT18
TRIM37
Gene Name
nudix (nucleoside diphosphate linked moiety X)-type motif 18
tripartite motif containing 37
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Cytoplasm
Peroxisome
Cytosol
Aggresome
ESC/E(Z) Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Magnesium Ion Binding
Protein Binding
8-oxo-dGDP Phosphatase Activity
8-oxo-GDP Phosphatase Activity
8-hydroxy-dADP Phosphatase Activity
Chromatin Binding
Ubiquitin-protein Transferase Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Biological Process
Nucleobase-containing Small Molecule Catabolic Process
Small Molecule Metabolic Process
DADP Catabolic Process
DGDP Catabolic Process
GDP Catabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of NF-kappaB Transcription Factor Activity
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Negative Regulation Of Centriole Replication
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Autoubiquitination
Aggresome Assembly
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Testicular germ cell tumor (
23666239
)
Protein-Protein Interactions
34 interactors:
APIP
COIL
CUTC
DCTD
DHPS
DUT
EVI5L
GLUL
GNMT
GSE1
HSD17B14
KCTD13
KCTD17
KHDRBS3
KRT15
KRTAP4-12
KXD1
NADK
NAT9
NT5C2
PAICS
PCBD1
PSME3
RAB3IL1
RABAC1
RAD54B
RWDD1
SDPR
TARBP2
TERF2IP
TIFA
TRAF2
TRIM37
ZBED1
59 interactors:
ANKRD11
APEX2
APTX
ARNT2
BYSL
CCDC33
CDC20B
CDK5RAP2
COPB1
CWF19L2
DDX6
DLGAP5
EWSR1
FAM107A
FAM124B
FAM161A
FAM50B
FXR2
KAT5
KIAA0408
KIF9
LTBR
MAGEB18
MCM10
MCRS1
NGFR
NUDT18
PBK
PNKP
PRC1
RASD1
RHPN1
RIBC2
RPL9
SCNM1
SSX2IP
TANK
TCEB3B
TNFRSF1B
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
TRAF6
UBASH3A
UBB
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2U
ZMAT2
ZNF329
ZNF417
ZNF655
Entrez ID
79873
4591
HPRD ID
07992
05463
Ensembl ID
ENSG00000108395
Uniprot IDs
Q6ZVK8
A8K0V9
A8K8U4
F8WEE6
O94972
PDB IDs
3GG6
3LRQ
Enriched GO Terms of Interacting Partners
?
Protein Homooligomerization
Protein Oligomerization
Nucleoside Metabolic Process
Protein Tetramerization
Nucleobase-containing Small Molecule Metabolic Process
Protein Complex Assembly
Cellular Nitrogen Compound Metabolic Process
Cellular Component Assembly
Protein Homotetramerization
Nitrogen Compound Metabolic Process
Catabolic Process
Small Molecule Metabolic Process
S-adenosylmethionine Metabolic Process
Purine Nucleoside Metabolic Process
Methionine Metabolic Process
Regulation Of Protein Homodimerization Activity
IMP Metabolic Process
Alpha-amino Acid Metabolic Process
Nucleotide Biosynthetic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Nucleotide Metabolic Process
Polyamine Metabolic Process
Cofactor Metabolic Process
Nucleobase-containing Compound Metabolic Process
Pyrimidine Nucleobase Metabolic Process
Protein Autoubiquitination
Purine Nucleobase Metabolic Process
Sulfur Amino Acid Metabolic Process
DUMP Biosynthetic Process
Deoxyhypusine Biosynthetic Process From Spermidine
DUTP Catabolic Process
Negative Regulation Of DNA Recombination At Telomere
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Pyrimidine Nucleoside Biosynthetic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Amino Acid Metabolic Process
I-kappaB Kinase/NF-kappaB Signaling
Glutamine Biosynthetic Process
MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA
Spermidine Catabolic Process
L-methionine Biosynthetic Process From S-adenosylmethionine
Cellular Modified Amino Acid Metabolic Process
Pyrimidine Nucleotide Metabolic Process
Pyrimidine Nucleoside Metabolic Process
Targeting Of MRNA For Destruction Involved In RNA Interference
DUMP Metabolic Process
NADP Biosynthetic Process
DUTP Metabolic Process
Negative Regulation Of Cilium Assembly
Protein Polyubiquitination
TRIF-dependent Toll-like Receptor Signaling Pathway
Protein K48-linked Ubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Cellular Macromolecule Catabolic Process
Regulation Of Innate Immune Response
Protein K11-linked Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Protein K63-linked Ubiquitination
Cellular Response To Stress
Catabolic Process
Polynucleotide 3' Dephosphorylation
Apoptotic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Protein Catabolic Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of DNA-templated Transcription In Response To Stress
Programmed Cell Death
I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Mitotic Cell Cycle Phase Transition
Cellular Response To DNA Damage Stimulus
Regulation Of Cell Cycle Phase Transition
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
Cell Death
Death
Activation Of NF-kappaB-inducing Kinase Activity
Modification-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of NIK/NF-kappaB Signaling
Cellular Protein Catabolic Process
DNA Repair
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Proteolysis
Regulation Of Stress-activated MAPK Cascade
NIK/NF-kappaB Signaling
Regulation Of NIK/NF-kappaB Signaling
Regulation Of Metabolic Process
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