NUDT18 and DCTD

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		NUDT18	DCTD
Gene Name		nudix (nucleoside diphosphate linked moiety X)-type motif 18	dCMP deaminase
Image
Gene Ontology Annotations	Cellular Component	Cytosol	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Protein Binding 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity	DCMP Deaminase Activity Zinc Ion Binding
	Biological Process	Nucleobase-containing Small Molecule Catabolic Process Small Molecule Metabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process Nucleobase-containing Small Molecule Metabolic Process	Pyrimidine Nucleobase Metabolic Process Pyrimidine Nucleotide Metabolic Process Nucleotide Biosynthetic Process Small Molecule Metabolic Process Pyrimidine Nucleoside Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways			Pyrimidine biosynthesis Pyrimidine metabolism Metabolism of nucleotides
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Wegener's granulomatosis ( 23740775)
Protein-Protein Interactions		34 interactors: APIP COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 SDPR TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1	9 interactors: CEP76 FGF12 GORASP2 LNX1 MALSU1 NIF3L1 NUDT18 SDCBP TXN2
Entrez ID		79873	1635
HPRD ID		07992	09623
Ensembl ID			ENSG00000129187
Uniprot IDs		Q6ZVK8	P32321
PDB IDs		3GG6	2W4L
Enriched GO Terms of Interacting Partners?		Protein Homooligomerization Protein Oligomerization Nucleoside Metabolic Process Protein Tetramerization Nucleobase-containing Small Molecule Metabolic Process Protein Complex Assembly Cellular Nitrogen Compound Metabolic Process Cellular Component Assembly Protein Homotetramerization Nitrogen Compound Metabolic Process Catabolic Process Small Molecule Metabolic Process S-adenosylmethionine Metabolic Process Purine Nucleoside Metabolic Process Methionine Metabolic Process Regulation Of Protein Homodimerization Activity IMP Metabolic Process Alpha-amino Acid Metabolic Process Nucleotide Biosynthetic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Nucleotide Metabolic Process Polyamine Metabolic Process Cofactor Metabolic Process Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Metabolic Process Protein Autoubiquitination Purine Nucleobase Metabolic Process Sulfur Amino Acid Metabolic Process DUMP Biosynthetic Process Deoxyhypusine Biosynthetic Process From Spermidine DUTP Catabolic Process Negative Regulation Of DNA Recombination At Telomere Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Pyrimidine Nucleoside Biosynthetic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Amino Acid Metabolic Process I-kappaB Kinase/NF-kappaB Signaling Glutamine Biosynthetic Process MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Spermidine Catabolic Process L-methionine Biosynthetic Process From S-adenosylmethionine Cellular Modified Amino Acid Metabolic Process Pyrimidine Nucleotide Metabolic Process Pyrimidine Nucleoside Metabolic Process Targeting Of MRNA For Destruction Involved In RNA Interference DUMP Metabolic Process NADP Biosynthetic Process DUTP Metabolic Process Negative Regulation Of Cilium Assembly	GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process Negative Regulation Of Mitochondrial Translation 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Dihydrobiopterin Metabolic Process Negative Regulation Of Ribosome Biogenesis Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Extracellular Vesicular Exosome Assembly Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process Ribonucleoside Diphosphate Catabolic Process Nucleoside Diphosphate Catabolic Process Regulation Of Mitochondrial Translation Regulation Of Organelle Organization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Deoxyribonucleoside Diphosphate Metabolic Process Regulation Of Centriole Replication Substrate-dependent Cell Migration, Cell Extension Purine Ribonucleoside Catabolic Process
Tagcloud ?			catabolism consequent cytidine deaminase deoxycytidine deoxyguanosine deoxyribonucleoside deoxyribonucleosides deoxyribonucleotide depletion disrupt dn dns dntp dntps encephalomyopathy immucillin mngie mtdna neurogastrointestinal nucleoside phosphorylase purine spite supplements tetrahydrouridine thu thymidine triphosphates
Tagcloud (Difference) ?			catabolism consequent cytidine deaminase deoxycytidine deoxyguanosine deoxyribonucleoside deoxyribonucleosides deoxyribonucleotide depletion disrupt dn dns dntp dntps encephalomyopathy immucillin mngie mtdna neurogastrointestinal nucleoside phosphorylase purine spite supplements tetrahydrouridine thu thymidine triphosphates
Tagcloud (Intersection) ?