NUDT18 and CUTC

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		NUDT18	CUTC
Gene Name		nudix (nucleoside diphosphate linked moiety X)-type motif 18	cutC copper transporter
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Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Magnesium Ion Binding Protein Binding 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity	Copper Ion Binding
	Biological Process	Nucleobase-containing Small Molecule Catabolic Process Small Molecule Metabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process Nucleobase-containing Small Molecule Metabolic Process	Copper Ion Transport Protein Tetramerization Copper Ion Homeostasis
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 22412388) Obesity-related traits ( 23251661)
Protein-Protein Interactions		34 interactors: APIP COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 SDPR TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1	11 interactors: ASCC2 BCL6 CEP76 LNX1 NADSYN1 NIF3L1 NUDT18 PIM2 SDCBP SLC27A6 SPG21
Entrez ID		79873	51076
HPRD ID		07992	13100
Ensembl ID			ENSG00000119929
Uniprot IDs		Q6ZVK8	Q9NTM9
PDB IDs		3GG6	3IWP
Enriched GO Terms of Interacting Partners?		Protein Homooligomerization Protein Oligomerization Nucleoside Metabolic Process Protein Tetramerization Nucleobase-containing Small Molecule Metabolic Process Protein Complex Assembly Cellular Nitrogen Compound Metabolic Process Cellular Component Assembly Protein Homotetramerization Nitrogen Compound Metabolic Process Catabolic Process Small Molecule Metabolic Process S-adenosylmethionine Metabolic Process Purine Nucleoside Metabolic Process Methionine Metabolic Process Regulation Of Protein Homodimerization Activity IMP Metabolic Process Alpha-amino Acid Metabolic Process Nucleotide Biosynthetic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Nucleotide Metabolic Process Polyamine Metabolic Process Cofactor Metabolic Process Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Metabolic Process Protein Autoubiquitination Purine Nucleobase Metabolic Process Sulfur Amino Acid Metabolic Process DUMP Biosynthetic Process Deoxyhypusine Biosynthetic Process From Spermidine DUTP Catabolic Process Negative Regulation Of DNA Recombination At Telomere Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Pyrimidine Nucleoside Biosynthetic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Amino Acid Metabolic Process I-kappaB Kinase/NF-kappaB Signaling Glutamine Biosynthetic Process MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Spermidine Catabolic Process L-methionine Biosynthetic Process From S-adenosylmethionine Cellular Modified Amino Acid Metabolic Process Pyrimidine Nucleotide Metabolic Process Pyrimidine Nucleoside Metabolic Process Targeting Of MRNA For Destruction Involved In RNA Interference DUMP Metabolic Process NADP Biosynthetic Process DUTP Metabolic Process Negative Regulation Of Cilium Assembly	GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Negative Regulation Of Mast Cell Cytokine Production Negative Regulation Of Isotype Switching To IgE Isotypes Dihydrobiopterin Metabolic Process Negative Regulation Of T-helper 2 Cell Differentiation Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Extracellular Vesicular Exosome Assembly Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process
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