NUDT18 and RAB3IL1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		NUDT18	RAB3IL1
Description		nudix hydrolase 18	RAB3A interacting protein like 1
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GO Annotations	Cellular Component	Cytosol	Cytosol
	Molecular Function	Protein Binding Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Nucleotide Metabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process Nucleobase-containing Small Molecule Metabolic Process	Protein Transport
Pathways			RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS			Aspartate aminotransferase levels ( 33547301) Metabolite levels ( 23823483) Oleic acid (18:1n-9) levels ( 23362303) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		34 interacting genes: APIP CAVIN2 COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1	27 interacting genes: C14orf119 C2orf68 CCDC57 COG6 CTDSP1 CYSRT1 EXOC8 FHL5 HSF2BP IP6K1 KRT34 KRT40 KRTAP6-3 MAP3K1 MTUS2 NBPF19 NOTCH2NLA NUDT18 PSMA3 RAB11A RAB3A RAB3IP RAB8A SATB2 STX1A TIGD7 TTC7B
Entrez ID		79873	5866
HPRD ID		07992	10181
Ensembl ID		ENSG00000275074	ENSG00000167994
Uniprot IDs		Q6ZVK8	Q8TBN0
PDB IDs		3GG6 4HVY	4LI0
Enriched GO Terms of Interacting Partners?		Identical Protein Binding DUMP Biosynthetic Process DTMP Biosynthetic Process Pyrimidine Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleoside Monophosphate Metabolic Process Negative Regulation Of Defense Response To Virus By Host Protein Complex Oligomerization Protein Homooligomerization Pyrimidine Deoxyribonucleotide Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Deoxyribonucleotide Metabolic Process Cytosol Nucleoside Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Protein Binding Amino Acid Biosynthetic Process L-amino Acid Metabolic Process Small Molecule Metabolic Process Deoxyribonucleotide Biosynthetic Process 2'-deoxyribonucleotide Biosynthetic Process Methionine Metabolic Process Negative Regulation Of Defense Response To Virus Alpha-amino Acid Metabolic Process Protein-containing Complex Assembly IMP Metabolic Process Nucleotide Biosynthetic Process Purine Nucleobase Metabolic Process Protein Tetramerization Nucleobase-containing Small Molecule Metabolic Process Nucleotide Metabolic Process Purine Nucleoside Metabolic Process Pyrimidine Nucleotide Biosynthetic Process Deoxyhypusine Synthase Activity Deoxyribose Phosphate Catabolic Process Deoxyribonucleotide Catabolic Process DUTP Catabolic Process DUTP Diphosphatase Activity Amino Acid Metabolic Process Intracellular Ammonium Homeostasis Tumor Necrosis Factor Receptor Binding Regulation Of SiRNA Processing Protein-containing Complex Organization TORC2 Complex Disassembly Protein Autosumoylation Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity GMP Metabolic Process Phosphoribosylaminoimidazole Carboxylase Activity Nucleoside Phosphotransferase Activity GMP Catabolic Process To Guanine Tubulin N-terminal-methionine Acetyltransferase Activity	Membrane Docking Organelle Localization By Membrane Tethering Vesicle Docking Involved In Exocytosis Myosin V Binding Vesicle Docking Vesicle-mediated Transport In Synapse Exocytosis Vesicle-mediated Transport To The Plasma Membrane Organelle Localization Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Vesicle Organization Regulation Of Neuronal Synaptic Plasticity Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Neurotransmitter Receptor Transport To Plasma Membrane Golgi To Plasma Membrane Transport Localization Within Membrane Endosome To Plasma Membrane Protein Transport Neurotransmitter Receptor Transport Secretion By Cell Post-Golgi Vesicle-mediated Transport Trans-Golgi Network Membrane Regulation Of Long-term Neuronal Synaptic Plasticity Organelle Organization Synaptic Vesicle Protein Localization To Postsynapse Protein Localization To Postsynaptic Membrane Secretion Protein Transport Protein Localization To Membrane Calcium-ion Regulated Exocytosis Regulation Of Presynaptic Dense Core Granule Exocytosis Synaptic Vesicle Exocytosis Evoked Neurotransmitter Secretion Synaptic Vesicle Membrane Myosin Head/neck Binding Synaptic Vesicle Endosomal Processing Golgi Vesicle Transport 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process Regulation Of Calcium Ion-dependent Exocytosis Intermediate Filament Vesicle-mediated Transport Centriole Golgi Vesicle Fusion To Target Membrane Receptor Localization To Synapse Insulin Secretion
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