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FYCO1 and MAP1LC3B
Number of citations of the paper that reports this interaction (PMID
23043107
)
9
Data Source:
BioGRID
(unspecified method)
FYCO1
MAP1LC3B
Gene Name
FYVE and coiled-coil domain containing 1
microtubule-associated protein 1 light chain 3 beta
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Lysosome
Late Endosome
Autophagic Vacuole
Membrane
Integral Component Of Membrane
Cytoplasmic Vesicle
Pre-autophagosomal Structure
Autophagic Vacuole Membrane
Intracellular
Autophagic Vacuole
Cytosol
Microtubule
Axoneme
Endomembrane System
Extrinsic Component Of Membrane
Organelle Membrane
Cytoplasmic Vesicle
Molecular Function
Protein Binding
Metal Ion Binding
Protein Binding
Microtubule Binding
GABA Receptor Binding
Biological Process
Plus-end-directed Vesicle Transport Along Microtubule
Autophagic Vacuole Assembly
Mitochondrion Degradation
Cellular Response To Nitrogen Starvation
Nucleophagy
Membrane Fusion
Pathways
Drugs
Diseases
GWAS
Major depressive disorder (
22472876
)
Protein-Protein Interactions
5 interactors:
APP
KDM1A
MAP1LC3B
PRMT6
RAF1
50 interactors:
AAMP
ADD1
ADNP
ARFGAP1
ATG3
ATG4A
ATG4B
ATG7
BNIP3
BRD3
CASP8
CCSER2
CLTA
DBI
DBN1
DNMT3B
EED
EPS8
FAM134A
FAM65A
FUNDC1
FYCO1
GABARAPL2
GORASP2
KBTBD7
KLHL5
KXD1
LUC7L2
MKRN1
MRFAP1
MYBL2
NHP2L1
RAD1
RAP1GAP
RPLP1
SAFB
SHFM1
SMARCB1
SPAG9
SQSTM1
TAF7
TAX1BP1
TBC1D17
TBC1D25
TBC1D9
TBC1D9B
THAP7
TMOD3
TNIP1
UPF2
Entrez ID
79443
81631
HPRD ID
06215
14358
Ensembl ID
ENSG00000163820
ENSG00000140941
Uniprot IDs
B7ZKT7
Q9BQS8
H6UMI0
Q658J6
Q9GZQ8
PDB IDs
1V49
2LUE
2ZJD
3VTU
3VTV
3VTW
Enriched GO Terms of Interacting Partners
?
Blood Coagulation
Hemostasis
Response To Stress
Regulation Of Body Fluid Levels
Wound Healing
Death-inducing Signaling Complex Assembly
Regulation Of Primitive Erythrocyte Differentiation
Response To Wounding
Negative Regulation Of Cellular Metabolic Process
Regulation Of Protein Binding
Negative Regulation Of Cellular Protein Metabolic Process
Histone H3-R2 Methylation
Synaptic Growth At Neuromuscular Junction
Negative Regulation Of Protein Metabolic Process
Collateral Sprouting In Absence Of Injury
Platelet Activation
Collateral Sprouting
Axon Midline Choice Point Recognition
Negative Regulation Of Apoptotic Signaling Pathway
Regulation Of Binding
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of Endopeptidase Activity
Negative Regulation Of Peptidase Activity
Axon Choice Point Recognition
Organelle Organization
Negative Regulation Of Histone H3-K4 Methylation
Histone H3-K9 Demethylation
Histone H3-K4 Demethylation
Cellular Protein Modification Process
Neuron Remodeling
Positive Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Proteolysis
Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine
Negative Regulation Of Protein Processing
Positive Regulation Of Hormone Biosynthetic Process
Regulation Of Endopeptidase Activity
Axon Guidance
Negative Regulation Of Histone H3-K9 Methylation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Cell Differentiation
Histone Modification
Regulation Of Cellular Amino Acid Metabolic Process
Negative Regulation Of Hydrolase Activity
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Protein Processing
Histone H4-R3 Methylation
Regulation Of Peptidase Activity
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Granulocyte Differentiation
Autophagy
Mitochondrion Degradation
Organelle Disassembly
Nucleophagy
Cellular Response To Nitrogen Starvation
Macroautophagy
Regulation Of Organelle Organization
Cellular Response To Starvation
Positive Regulation Of Metabolic Process
Organelle Organization
Positive Regulation Of Autophagy
Response To Starvation
Cellular Response To Nutrient Levels
Autophagic Vacuole Assembly
Cellular Response To Extracellular Stimulus
Cellular Response To Stress
Intracellular Transport
Catabolic Process
Mitochondrion Organization
Regulation Of Cellular Component Organization
C-terminal Protein Lipidation
Protein Delipidation
Membrane Organization
Response To Stress
Vacuole Organization
Regulation Of Autophagy
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Complex Disassembly
Establishment Of Localization In Cell
Regulation Of Histone Modification
Actin Filament Capping
Positive Regulation Of Rab GTPase Activity
Regulation Of Rab GTPase Activity
Regulation Of Rab Protein Signal Transduction
Mitochondrial Fragmentation Involved In Apoptotic Process
Positive Regulation Of Hydrolase Activity
Cellular Localization
Negative Regulation Of Actin Filament Depolymerization
Response To Nutrient Levels
Cellular Component Assembly
Protein Localization
Regulation Of Ras Protein Signal Transduction
Response To Extracellular Stimulus
Response To Cobalt Ion
Protein Targeting To Membrane
Regulation Of Actin Filament Depolymerization
Organelle Assembly
Negative Regulation Of Actin Filament Polymerization
Positive Regulation Of Macroautophagy
Negative Regulation Of Histone Acetylation
Tagcloud
?
akt1
antipsychotic
atg
atg12
atg4b
atg5
atg7
autophagic
autophagosome
autophagosomes
autophagy
bak1
bcl2l11
becn1
cdkn1a
cdkn1b
chloroquine
colocalization
dysfunctional
gabarap
henceforth
olanzapine
overtly
pmaip1
sqstm1
sy5y
trp53
unmask
Tagcloud (Difference)
?
akt1
antipsychotic
atg
atg12
atg4b
atg5
atg7
autophagic
autophagosome
autophagosomes
autophagy
bak1
bcl2l11
becn1
cdkn1a
cdkn1b
chloroquine
colocalization
dysfunctional
gabarap
henceforth
olanzapine
overtly
pmaip1
sqstm1
sy5y
trp53
unmask
Tagcloud (Intersection)
?