MAP1LC3B and SAFB

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MAP1LC3B	SAFB
Gene Name		microtubule-associated protein 1 light chain 3 beta	scaffold attachment factor B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Cytosol Microtubule Axoneme Endomembrane System Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Microtubule Binding GABA Receptor Binding	Nucleotide Binding Core Promoter Binding Chromatin Binding Double-stranded DNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	Chromatin Organization Transcription, DNA-templated Intracellular Estrogen Receptor Signaling Pathway Growth Hormone Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)
Protein-Protein Interactions		50 interactors: AAMP ADD1 ADNP ARFGAP1 ATG3 ATG4A ATG4B ATG7 BNIP3 BRD3 CASP8 CCSER2 CLTA DBI DBN1 DNMT3B EED EPS8 FAM134A FAM65A FUNDC1 FYCO1 GABARAPL2 GORASP2 KBTBD7 KLHL5 KXD1 LUC7L2 MKRN1 MRFAP1 MYBL2 NHP2L1 RAD1 RAP1GAP RPLP1 SAFB SHFM1 SMARCB1 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 UPF2	21 interactors: ABHD16A CDC37 CHD1 CHD3 CLK1 CSNK2A1 CYCS ESR1 HNRNPA1 HNRNPD HNRNPK IL7R MAP1LC3B NCOR1 POLR2A SAFB2 SREK1 SRPK1 SRSF9 TAF15 TJP2
Entrez ID		81631	6294
HPRD ID		14358	04205
Ensembl ID		ENSG00000140941	ENSG00000160633
Uniprot IDs		H6UMI0 Q658J6 Q9GZQ8	Q15424
PDB IDs		1V49 2LUE 2ZJD 3VTU 3VTV 3VTW
Enriched GO Terms of Interacting Partners?		Autophagy Mitochondrion Degradation Organelle Disassembly Nucleophagy Cellular Response To Nitrogen Starvation Macroautophagy Regulation Of Organelle Organization Cellular Response To Starvation Positive Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Autophagy Response To Starvation Cellular Response To Nutrient Levels Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Cellular Response To Stress Intracellular Transport Catabolic Process Mitochondrion Organization Regulation Of Cellular Component Organization C-terminal Protein Lipidation Protein Delipidation Membrane Organization Response To Stress Vacuole Organization Regulation Of Autophagy Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Complex Disassembly Establishment Of Localization In Cell Regulation Of Histone Modification Actin Filament Capping Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Hydrolase Activity Cellular Localization Negative Regulation Of Actin Filament Depolymerization Response To Nutrient Levels Cellular Component Assembly Protein Localization Regulation Of Ras Protein Signal Transduction Response To Extracellular Stimulus Response To Cobalt Ion Protein Targeting To Membrane Regulation Of Actin Filament Depolymerization Organelle Assembly Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Macroautophagy Negative Regulation Of Histone Acetylation	RNA Splicing Nucleobase-containing Compound Metabolic Process RNA Metabolic Process MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process MRNA Metabolic Process RNA Processing Nitrogen Compound Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated RNA Biosynthetic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Chromatin Organization Regulation Of Metabolic Process DNA-templated Transcription, Initiation Cellular Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Viral Process Rhythmic Process Chromatin Modification Metabolic Process Chromosome Organization Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Metabolic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated DNA Conformation Change Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Interleukin-7-mediated Signaling Pathway Transcription, RNA-templated Positive Regulation Of Viral Process RNA Export From Nucleus Execution Phase Of Apoptosis
Tagcloud ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	array bank comparing consistently differentially electrophoresis emphasizing follicular gel hundred luca lymphoma lymphomagenesis mad1l1 maldi mantle modest pooling programs proteome rad50 referenced relevance search seventy spots standardized tof translational
Tagcloud (Difference) ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	array bank comparing consistently differentially electrophoresis emphasizing follicular gel hundred luca lymphoma lymphomagenesis mad1l1 maldi mantle modest pooling programs proteome rad50 referenced relevance search seventy spots standardized tof translational
Tagcloud (Intersection) ?