ZYX and ZHX1

Number of citations of the paper that reports this interaction (PMID 12659632)
9

Data Source:
BioGRID (two hybrid)

		ZYX	ZHX1
Gene Name		zyxin	zinc fingers and homeoboxes 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Adherens Junction Focal Adhesion	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Poly(A) RNA Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Cell Adhesion Cell-matrix Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Viral Process Stress Fiber Assembly Regulation Of Inflammatory Response	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: ACTN1 ATXN1 BSPRY ENAH HIPK3 IMP3 LASP1 LATS1 LIN7A NEBL NEDD9 OPRM1 PDLIM5 PHF21A RABEPK RGS2 RPH3AL RTN4IP1 SREBF2 TES VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384	50 interactors: AKR1C3 AKT1 ATXN1 BARD1 BCL2L1 BHLHE40 BID CHD3 CREB1 CSNK2A1 DDX39B DLST DYNLL1 EFNA2 ELL GADD45A GNG11 GSK3B HSPE1 IDH1 LAMA4 LYAR MPHOSPH6 NACA NFYA PAFAH1B3 PEX14 PIAS4 PIGC PNP PRPF40A PSMD11 SAT1 SERPINB9 SUMO2 TAL1 TALDO1 TARDBP TERF1 TNFRSF10C TOLLIP TP53 UTP3 VIM WDR33 ZHX2 ZHX3 ZMYND11 ZNF33B ZYX
Entrez ID		7791	11244
HPRD ID		03592	10379
Ensembl ID		ENSG00000159840	ENSG00000165156
Uniprot IDs		Q15942 Q96AF9	Q9UKY1
PDB IDs			2ECB 2GHF 2LY9 3NAR
Enriched GO Terms of Interacting Partners?		Actin Filament Organization Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Transport Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of CAMP-mediated Signaling Negative Regulation Of Transferase Activity Integrin-mediated Signaling Pathway Negative Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Actin Cytoskeleton Organization Wound Healing Negative Regulation Of Protein Serine/threonine Kinase Activity Antigen Receptor-mediated Signaling Pathway Exocytosis Actin Filament-based Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Response To Wounding Negative Regulation Of Transport Negative Regulation Of Signal Transduction Blood Coagulation Hemostasis Regulation Of Cellular Process Platelet Activation Negative Regulation Of Wnt Protein Secretion Cardiac Muscle Thin Filament Assembly Peptidyl-threonine Phosphorylation Negative Regulation Of Signaling Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Immune Response-regulating Signaling Pathway Neutrophil Chemotaxis Negative Regulation Of Cellular Protein Metabolic Process Neutrophil Migration Regulation Of Signal Transduction Positive Regulation Of Rac GTPase Activity Cell Differentiation Granulocyte Chemotaxis Secretion By Cell Regulation Of Immune Response Developmental Process Actin Filament Bundle Assembly Negative Regulation Of Protein Metabolic Process Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process	Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Cell Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cell Death Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Viral Process Regulation Of Mitochondrion Organization Negative Regulation Of Biosynthetic Process Apoptotic Process RNA Metabolic Process Programmed Cell Death Cell Death Death Cellular Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Transcription, DNA-templated Negative Regulation Of Gene Expression Cell Cycle Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Rhythmic Process Negative Regulation Of Cell Cycle Developmental Process Positive Regulation Of Protein Metabolic Process Biosynthetic Process Positive Regulation Of Protein Catabolic Process Cell Cycle Process Regulation Of Cell Cycle Process Regulation Of Proteolysis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Cellular Process Negative Regulation Of Transcription, DNA-templated
Tagcloud ?		ajuba apical branch dachs dco distinctive epistasis extend fat fundamental hippo incomplete intercellular jub lim localizes mechanical myosin oncogenesis overlap overlaps peaks raises share vertices ways yorkie zyx102 zyxin	199a 3p accumulating bound carcinogenesis direct dramatically epigenetic fingers gastric gc homeoboxes inversely involve micrornas mir mirnas n87 nci oncogenic regulator regulators restoring sgc suppressed untranslated upregulated utr zinc
Tagcloud (Difference) ?		ajuba apical branch dachs dco distinctive epistasis extend fat fundamental hippo incomplete intercellular jub lim localizes mechanical myosin oncogenesis overlap overlaps peaks raises share vertices ways yorkie zyx102 zyxin	199a 3p accumulating bound carcinogenesis direct dramatically epigenetic fingers gastric gc homeoboxes inversely involve micrornas mir mirnas n87 nci oncogenic regulator regulators restoring sgc suppressed untranslated upregulated utr zinc
Tagcloud (Intersection) ?