ZHX1 and UTP3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZHX1	UTP3
Gene Name		zinc fingers and homeoboxes 1	UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleolus Small-subunit Processome
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding Protein Heterodimerization Activity	Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Brain Development Chromatin Modification
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		50 interactors: AKR1C3 AKT1 ATXN1 BARD1 BCL2L1 BHLHE40 BID CHD3 CREB1 CSNK2A1 DDX39B DLST DYNLL1 EFNA2 ELL GADD45A GNG11 GSK3B HSPE1 IDH1 LAMA4 LYAR MPHOSPH6 NACA NFYA PAFAH1B3 PEX14 PIAS4 PIGC PNP PRPF40A PSMD11 SAT1 SERPINB9 SUMO2 TAL1 TALDO1 TARDBP TERF1 TNFRSF10C TOLLIP TP53 UTP3 VIM WDR33 ZHX2 ZHX3 ZMYND11 ZNF33B ZYX	5 interactors: CDCA7L DVL3 HAP1 PTN ZHX1
Entrez ID		11244	57050
HPRD ID		10379	18016
Ensembl ID		ENSG00000165156	ENSG00000132467
Uniprot IDs		Q9UKY1	Q9NQZ2
PDB IDs		2ECB 2GHF 2LY9 3NAR
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Cell Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cell Death Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Viral Process Regulation Of Mitochondrion Organization Negative Regulation Of Biosynthetic Process Apoptotic Process RNA Metabolic Process Programmed Cell Death Cell Death Death Cellular Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Transcription, DNA-templated Negative Regulation Of Gene Expression Cell Cycle Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Rhythmic Process Negative Regulation Of Cell Cycle Developmental Process Positive Regulation Of Protein Metabolic Process Biosynthetic Process Positive Regulation Of Protein Catabolic Process Cell Cycle Process Regulation Of Cell Cycle Process Regulation Of Proteolysis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Cellular Process Negative Regulation Of Transcription, DNA-templated	Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Cilium Assembly Non-canonical Wnt Signaling Pathway Via JNK Cascade Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Non-canonical Wnt Signaling Pathway Via MAPK Cascade Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Hypothalamus Cell Differentiation Negative Regulation Of Beta-amyloid Formation Retrograde Axon Cargo Transport Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Negative Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Microtubule-based Movement Outflow Tract Septum Morphogenesis Positive Regulation Of Synaptic Transmission, GABAergic Regulation Of Metabolic Process Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Smooth Muscle Cell Migration DNA Demethylation Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Telomere Maintenance Via Semi-conservative Replication Response To Drug Regulation Of Beta-amyloid Formation Regulation Of Transcription, DNA-templated Regulation Of Cilium Assembly Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear DNA Replication Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Amyloid Precursor Protein Catabolic Process Telomere Maintenance Via Recombination Positive Regulation Of ERBB Signaling Pathway Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Cochlea Morphogenesis Hypothalamus Development Positive Regulation Of Organelle Assembly Positive Regulation Of Cell Cycle G1/S Phase Transition Regulation Of RNA Metabolic Process Anterograde Axon Cargo Transport Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Non-canonical Wnt Signaling Pathway Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cation Channel Activity DNA Catabolic Process, Exonucleolytic
Tagcloud ?		199a 3p accumulating bound carcinogenesis direct dramatically epigenetic fingers gastric gc homeoboxes inversely involve micrornas mir mirnas n87 nci oncogenic regulator regulators restoring sgc suppressed untranslated upregulated utr zinc
Tagcloud (Difference) ?		199a 3p accumulating bound carcinogenesis direct dramatically epigenetic fingers gastric gc homeoboxes inversely involve micrornas mir mirnas n87 nci oncogenic regulator regulators restoring sgc suppressed untranslated upregulated utr zinc
Tagcloud (Intersection) ?