ZYX and LIN7A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZYX	LIN7A
Gene Name		zyxin	lin-7 homolog A (C. elegans)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Adherens Junction Focal Adhesion	Cell-cell Junction Tight Junction Postsynaptic Density Basolateral Plasma Membrane Neuron Projection Synapse Postsynaptic Membrane Extracellular Vesicular Exosome MPP7-DLG1-LIN7 Complex
	Molecular Function	Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Protein Binding PDZ Domain Binding L27 Domain Binding
	Biological Process	Cell Adhesion Cell-matrix Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Viral Process Stress Fiber Assembly Regulation Of Inflammatory Response	Protein Complex Assembly Exocytosis Neurotransmitter Secretion Asymmetric Protein Localization Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Synaptic Vesicle Transport Inner Ear Development Protein Localization To Basolateral Plasma Membrane
Pathways
Drugs
Diseases
GWAS			Dental caries ( 23259602)
Protein-Protein Interactions		27 interactors: ACTN1 ATXN1 BSPRY ENAH HIPK3 IMP3 LASP1 LATS1 LIN7A NEBL NEDD9 OPRM1 PDLIM5 PHF21A RABEPK RGS2 RPH3AL RTN4IP1 SREBF2 TES VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384	19 interactors: ABCA1 APP BAI1 BAIAP2 CASK DLG2 DLG3 DLG4 FAM9B GOLGA2 GRIN2B KCNJ12 MPP2 MPP3 MPP5 MPP6 NOTCH2NL SLC6A12 ZYX
Entrez ID		7791	8825
HPRD ID		03592	04542
Ensembl ID		ENSG00000159840	ENSG00000111052
Uniprot IDs		Q15942 Q96AF9	O14910
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Filament Organization Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Transport Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of CAMP-mediated Signaling Negative Regulation Of Transferase Activity Integrin-mediated Signaling Pathway Negative Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Actin Cytoskeleton Organization Wound Healing Negative Regulation Of Protein Serine/threonine Kinase Activity Antigen Receptor-mediated Signaling Pathway Exocytosis Actin Filament-based Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Response To Wounding Negative Regulation Of Transport Negative Regulation Of Signal Transduction Blood Coagulation Hemostasis Regulation Of Cellular Process Platelet Activation Negative Regulation Of Wnt Protein Secretion Cardiac Muscle Thin Filament Assembly Peptidyl-threonine Phosphorylation Negative Regulation Of Signaling Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Immune Response-regulating Signaling Pathway Neutrophil Chemotaxis Negative Regulation Of Cellular Protein Metabolic Process Neutrophil Migration Regulation Of Signal Transduction Positive Regulation Of Rac GTPase Activity Cell Differentiation Granulocyte Chemotaxis Secretion By Cell Regulation Of Immune Response Developmental Process Actin Filament Bundle Assembly Negative Regulation Of Protein Metabolic Process Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process	Nucleotide Phosphorylation Receptor Localization To Synapse Protein Localization To Synapse Axonogenesis Signaling Cell-cell Signaling Cell Communication Nucleotide Metabolic Process Axon Development Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Neuron Projection Morphogenesis Nucleobase-containing Small Molecule Metabolic Process Receptor Clustering Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Membrane Organization Cell Part Morphogenesis Cellular Component Assembly Neuron Development Signal Transduction Organophosphate Metabolic Process Secretion Cell Morphogenesis Cellular Response To Stimulus Neuron Differentiation Neurogenesis Neuromuscular Process Nervous System Development Suckling Behavior Cell Projection Organization Protein Localization To Membrane Dendrite Development Multicellular Organismal Development Small Molecule Metabolic Process Learning Axon Guidance Anatomical Structure Morphogenesis Establishment Or Maintenance Of Apical/basal Cell Polarity Cell Development Regulation Of Synaptic Plasticity Phosphorylation System Development Cell Differentiation Secretion By Cell Ionotropic Glutamate Receptor Signaling Pathway Developmental Process Generation Of Neurons Protein Localization To Myelin Sheath Abaxonal Region
Tagcloud ?		ajuba apical branch dachs dco distinctive epistasis extend fat fundamental hippo incomplete intercellular jub lim localizes mechanical myosin oncogenesis overlap overlaps peaks raises share vertices ways yorkie zyx102 zyxin	adherens associates cadherin carboxyl changing compartment deleted dimer dimerizes dlg1 guanylate homology insoluble junctions l27 lin7c localizes maguk members mpp7 pdz redistributes requiring stabilizes stabilizing stardust tripartite uncharacterized
Tagcloud (Difference) ?		ajuba apical branch dachs dco distinctive epistasis extend fat fundamental hippo incomplete intercellular jub lim mechanical myosin oncogenesis overlap overlaps peaks raises share vertices ways yorkie zyx102 zyxin	adherens associates cadherin carboxyl changing compartment deleted dimer dimerizes dlg1 guanylate homology insoluble junctions l27 lin7c maguk members mpp7 pdz redistributes requiring stabilizes stabilizing stardust tripartite uncharacterized
Tagcloud (Intersection) ?		localizes