ZYX and ZNF384

Number of citations of the paper that reports this interaction (PubMedID 16510139)
0

Data Source:
HPRD (in vivo, two hybrid)

		ZYX	ZNF384
Description		zyxin	zinc finger protein 384
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Actin Cytoskeleton Phagocytic Vesicle Anchoring Junction	Nucleus
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	DNA Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cell Adhesion Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Stress Fiber Assembly Cellular Response To Type II Interferon	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs		Artenimol
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) White blood cell count (basophil) ( 27863252)
Interacting Genes		36 interacting genes: ACTN1 ATXN1 BSPRY CASS4 CEBPA ENAH EVL HIPK3 IMP3 LAP3 LASP1 LATS1 LIN7A NEBL NEDD9 NME5 OPRM1 PDLIM5 PHF21A QRICH1 RABEPK RGS2 RPH3AL RTN4IP1 SIAH1 SREBF2 TES TUFT1 VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384 ZNF512B	10 interacting genes: CEBPE HOXC9 MBD1 PCBP1 POU6F2 TAF15 TRIM27 UBE2K VIM ZYX
Entrez ID		7791	171017
HPRD ID		03592	18332
Ensembl ID		ENSG00000159840	ENSG00000126746
Uniprot IDs		Q15942 Q96AF9	A0A804HJE2 Q8TF68
PDB IDs
Enriched GO Terms of Interacting Partners?		Focal Adhesion Profilin Binding Anchoring Junction Actin Filament Organization Actin Binding Postsynapse Regulation Of Cellular Component Size Cytoplasm Stress Fiber Supramolecular Fiber Organization Lymphocyte Migration Into Lymphoid Organs Positive Regulation Of Protein Tyrosine Kinase Activity Actin Polymerization Or Depolymerization Platelet Activation Cytoskeletal Protein Binding Cytoskeleton Lamellipodium Regulation Of Cell Size	Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Nucleus DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Cellular Response To Type II Interferon Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Sequence-specific Single Stranded DNA Binding Phagocytic Vesicle Cellular Response To Cytokine Stimulus Response To Type II Interferon DNA-templated Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Supramolecular Fiber Organization Nuclear Matrix Double-stranded Methylated DNA Binding Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Gene Expression Response To Peptide Response To Cytokine Free Ubiquitin Chain Polymerization Viral RNA Genome Replication Nucleic Acid Binding Phosphatidylinositol 3-kinase Inhibitor Activity Keratin Filament Binding Negative Regulation Of Gene Expression, Epigenetic Cellular Response To Lipopolysaccharide Lens Fiber Cell Development
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