ZYX and RPH3AL

Number of citations of the paper that reports this interaction (PMID 9367993)
14

Data Source:
HPRD (two hybrid, in vivo)

		ZYX	RPH3AL
Gene Name		zyxin	rabphilin 3A-like (without C2 domains)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Adherens Junction Focal Adhesion	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Cytoskeletal Protein Binding Rab GTPase Binding LIM Domain Binding Metal Ion Binding
	Biological Process	Cell Adhesion Cell-matrix Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Viral Process Stress Fiber Assembly Regulation Of Inflammatory Response	Intracellular Protein Transport Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Response To Drug Glucose Homeostasis Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Secretion
Pathways
Drugs
Diseases
GWAS			AIDS progression ( 21502085)
Protein-Protein Interactions		27 interactors: ACTN1 ATXN1 BSPRY ENAH HIPK3 IMP3 LASP1 LATS1 LIN7A NEBL NEDD9 OPRM1 PDLIM5 PHF21A RABEPK RGS2 RPH3AL RTN4IP1 SREBF2 TES VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384	13 interactors: MID2 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 TCEA3 UNC13B ZYX
Entrez ID		7791	9501
HPRD ID		03592	05345
Ensembl ID		ENSG00000159840	ENSG00000181031
Uniprot IDs		Q15942 Q96AF9	A8K7D5 Q9UNE2
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Filament Organization Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Transport Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of CAMP-mediated Signaling Negative Regulation Of Transferase Activity Integrin-mediated Signaling Pathway Negative Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Actin Cytoskeleton Organization Wound Healing Negative Regulation Of Protein Serine/threonine Kinase Activity Antigen Receptor-mediated Signaling Pathway Exocytosis Actin Filament-based Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Response To Wounding Negative Regulation Of Transport Negative Regulation Of Signal Transduction Blood Coagulation Hemostasis Regulation Of Cellular Process Platelet Activation Negative Regulation Of Wnt Protein Secretion Cardiac Muscle Thin Filament Assembly Peptidyl-threonine Phosphorylation Negative Regulation Of Signaling Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Immune Response-regulating Signaling Pathway Neutrophil Chemotaxis Negative Regulation Of Cellular Protein Metabolic Process Neutrophil Migration Regulation Of Signal Transduction Positive Regulation Of Rac GTPase Activity Cell Differentiation Granulocyte Chemotaxis Secretion By Cell Regulation Of Immune Response Developmental Process Actin Filament Bundle Assembly Negative Regulation Of Protein Metabolic Process Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process	Vesicle Docking Involved In Exocytosis Regulation Of Exocytosis Vesicle Docking Membrane Docking Protein Secretion Rab Protein Signal Transduction Exocytosis Establishment Of Vesicle Localization Vesicle Localization Regulation Of Vesicle-mediated Transport Regulation Of Secretion Neurotransmitter Secretion Synaptic Vesicle Transport Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Levels Secretion By Cell Neurotransmitter Transport Establishment Of Organelle Localization Cell-cell Signaling Synaptic Transmission Secretion Regulation Of Cellular Localization Ras Protein Signal Transduction Organelle Localization Cellular Protein Localization Positive Regulation Of Exocytosis Cellular Localization Protein Localization Intracellular Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Positive Regulation Of Secretion Small GTPase Mediated Signal Transduction Regulation Of Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Positive Regulation Of Transport Intracellular Signal Transduction Establishment Of Localization In Cell Positive Regulation Of Regulated Secretory Pathway Protein Transport Intracellular Transport Regulation Of Synaptic Transmission Peptidyl-cysteine Methylation Regulation Of Regulated Secretory Pathway Multivesicular Body Sorting Pathway Regulation Of Synaptic Plasticity Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Regulation Of Neurotransmitter Secretion Signaling Cell Communication
Tagcloud ?		ajuba apical branch dachs dco distinctive epistasis extend fat fundamental hippo incomplete intercellular jub lim localizes mechanical myosin oncogenesis overlap overlaps peaks raises share vertices ways yorkie zyx102 zyxin	artificial au bac breakpoints cafe cals cyto deletions dieker dysmorphisms emerges ends facial fosmid frames haploinsufficiency lait mdcr metrnl miller p1 pac preserved probes retardation sole spots subcloned unrevealed
Tagcloud (Difference) ?		ajuba apical branch dachs dco distinctive epistasis extend fat fundamental hippo incomplete intercellular jub lim localizes mechanical myosin oncogenesis overlap overlaps peaks raises share vertices ways yorkie zyx102 zyxin	artificial au bac breakpoints cafe cals cyto deletions dieker dysmorphisms emerges ends facial fosmid frames haploinsufficiency lait mdcr metrnl miller p1 pac preserved probes retardation sole spots subcloned unrevealed
Tagcloud (Intersection) ?