ZYX and PDLIM5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZYX	PDLIM5
Gene Name		zyxin	PDZ and LIM domain 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Adherens Junction Focal Adhesion	Cytosol Postsynaptic Density Actin Cytoskeleton Membrane Z Disc Cell Junction Neuron Projection Postsynaptic Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Actin Binding Protein Kinase C Binding Zinc Ion Binding Actinin Binding Protein N-terminus Binding
	Biological Process	Cell Adhesion Cell-matrix Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Viral Process Stress Fiber Assembly Regulation Of Inflammatory Response	Regulation Of Synapse Assembly Regulation Of Dendritic Spine Morphogenesis
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 19767753) Visceral fat ( 22589738)
Protein-Protein Interactions		27 interactors: ACTN1 ATXN1 BSPRY ENAH HIPK3 IMP3 LASP1 LATS1 LIN7A NEBL NEDD9 OPRM1 PDLIM5 PHF21A RABEPK RGS2 RPH3AL RTN4IP1 SREBF2 TES VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384	13 interactors: ACTB ACTN1 CACNA1B CCDC136 COIL GFI1B KRT40 KRTAP10-7 PRKCB PRKCE PRKCG TRIM39 ZYX
Entrez ID		7791	10611
HPRD ID		03592	05799
Ensembl ID		ENSG00000159840	ENSG00000163110
Uniprot IDs		Q15942 Q96AF9	B7Z481 B7Z8X5 Q96HC4
PDB IDs			2DAR 2UZC
Enriched GO Terms of Interacting Partners?		Actin Filament Organization Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Transport Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of CAMP-mediated Signaling Negative Regulation Of Transferase Activity Integrin-mediated Signaling Pathway Negative Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Actin Cytoskeleton Organization Wound Healing Negative Regulation Of Protein Serine/threonine Kinase Activity Antigen Receptor-mediated Signaling Pathway Exocytosis Actin Filament-based Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Response To Wounding Negative Regulation Of Transport Negative Regulation Of Signal Transduction Blood Coagulation Hemostasis Regulation Of Cellular Process Platelet Activation Negative Regulation Of Wnt Protein Secretion Cardiac Muscle Thin Filament Assembly Peptidyl-threonine Phosphorylation Negative Regulation Of Signaling Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Immune Response-regulating Signaling Pathway Neutrophil Chemotaxis Negative Regulation Of Cellular Protein Metabolic Process Neutrophil Migration Regulation Of Signal Transduction Positive Regulation Of Rac GTPase Activity Cell Differentiation Granulocyte Chemotaxis Secretion By Cell Regulation Of Immune Response Developmental Process Actin Filament Bundle Assembly Negative Regulation Of Protein Metabolic Process Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process	Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Pain Response To Morphine Immune Response-activating Cell Surface Receptor Signaling Pathway Activation Of Phospholipase C Activity Calcium Ion Transport Positive Regulation Of Phospholipase C Activity Cell-cell Signaling Actin Filament Bundle Assembly Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Phospholipase Activity Positive Regulation Of Cellular Glucuronidation Positive Regulation Of Mismatch Repair Regulation Of Phospholipase Activity Multicellular Organismal Response To Stress Adherens Junction Organization Positive Regulation Of Lipase Activity Response To Ammonium Ion Response To Stress Immune Response-regulating Signaling Pathway Immune System Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Adhesion Negative Regulation Of Protein Ubiquitination Regulation Of Mismatch Repair TRAM-dependent Toll-like Receptor 4 Signaling Pathway Histone H3-T6 Phosphorylation Negative Regulation Of Protein Catabolic Process Cellular Response To Growth Factor Stimulus Synaptic Transmission Behavior Response To Growth Factor Chromatin Modification Response To Alkaloid Positive Regulation Of Immune Response Protein Localization To Tight Junction Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway
Tagcloud ?		ajuba apical branch dachs dco distinctive epistasis extend fat fundamental hippo incomplete intercellular jub lim localizes mechanical myosin oncogenesis overlap overlaps peaks raises share vertices ways yorkie zyx102 zyxin	14e4 1c4 3h1 4d2 bands bmpr1b copy e5 hybridisation losses ontology pde6d ptc ptcs ptma slitrk1 slitrk5 slitrk6 srm t1 taf12 tp73 transgenics trk trp73 tumourigenesis twist2 unc5c ythdf2
Tagcloud (Difference) ?		ajuba apical branch dachs dco distinctive epistasis extend fat fundamental hippo incomplete intercellular jub lim localizes mechanical myosin oncogenesis overlap overlaps peaks raises share vertices ways yorkie zyx102 zyxin	14e4 1c4 3h1 4d2 bands bmpr1b copy e5 hybridisation losses ontology pde6d ptc ptcs ptma slitrk1 slitrk5 slitrk6 srm t1 taf12 tp73 transgenics trk trp73 tumourigenesis twist2 unc5c ythdf2
Tagcloud (Intersection) ?