ZYX and RABEPK

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		ZYX	RABEPK
Description		zyxin	Rab9 effector protein with kelch motifs
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Actin Cytoskeleton Phagocytic Vesicle Anchoring Junction	Cytoplasm Endosome Cytosol Endosome Membrane Membrane Transport Vesicle Trans-Golgi Network Membrane
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Cell Adhesion Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Stress Fiber Assembly Cellular Response To Type II Interferon	Receptor-mediated Endocytosis Vesicle Docking Involved In Exocytosis
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs		Artenimol
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) White blood cell count (basophil) ( 27863252)	Refractive error ( 32231278)
Interacting Genes		36 interacting genes: ACTN1 ATXN1 BSPRY CASS4 CEBPA ENAH EVL HIPK3 IMP3 LAP3 LASP1 LATS1 LIN7A NEBL NEDD9 NME5 OPRM1 PDLIM5 PHF21A QRICH1 RABEPK RGS2 RPH3AL RTN4IP1 SIAH1 SREBF2 TES TUFT1 VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384 ZNF512B	8 interacting genes: GLUL PIKFYVE POR PRKRA RAB9A TMEM98 TRIM55 ZYX
Entrez ID		7791	10244
HPRD ID		03592	09337
Ensembl ID		ENSG00000159840	ENSG00000136933
Uniprot IDs		Q15942 Q96AF9	A0A024R8A0 A0A0S2Z4Z5 Q7Z6M1
PDB IDs
Enriched GO Terms of Interacting Partners?		Focal Adhesion Profilin Binding Anchoring Junction Actin Filament Organization Actin Binding Postsynapse Regulation Of Cellular Component Size Cytoplasm Stress Fiber Supramolecular Fiber Organization Lymphocyte Migration Into Lymphoid Organs Positive Regulation Of Protein Tyrosine Kinase Activity Actin Polymerization Or Depolymerization Platelet Activation Cytoskeletal Protein Binding Cytoskeleton Lamellipodium Regulation Of Cell Size	Glutamine Synthetase Activity Intracellular Ammonium Homeostasis Glutamine Biosynthetic Process Iron-cytochrome-c Reductase Activity Positive Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Nitric Oxide Dioxygenase NAD(P)H Activity Nitrate Catabolic Process Enzyme Activator Activity Nitric Oxide Catabolic Process Organofluorine Metabolic Process Phagocytic Vesicle Phagocytic Vesicle Membrane Retrograde Transport, Endosome To Golgi Phosphatidylinositol 5-phosphate Metabolic Process 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate Metabolic Process Nitrate Metabolic Process NADPH-hemoprotein Reductase Activity 1-phosphatidylinositol-3-phosphate 5-kinase Activity 1-phosphatidylinositol-5-kinase Activity Cytosolic Transport Myeloid Leukocyte Migration Regulation Of Protein Localization To Nucleus Positive Regulation Of Steroid Hormone Biosynthetic Process Peptidyl-serine Autophosphorylation
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