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ZHX1 and TNFRSF10C
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
ZHX1
TNFRSF10C
Gene Name
zinc fingers and homeoboxes 1
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Integral Component Of Plasma Membrane
Anchored Component Of Membrane
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Corepressor Activity
Protein Binding
Metal Ion Binding
Protein Heterodimerization Activity
Transmembrane Signaling Receptor Activity
TRAIL Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Apoptotic Process
Signal Transduction
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
50 interactors:
AKR1C3
AKT1
ATXN1
BARD1
BCL2L1
BHLHE40
BID
CHD3
CREB1
CSNK2A1
DDX39B
DLST
DYNLL1
EFNA2
ELL
GADD45A
GNG11
GSK3B
HSPE1
IDH1
LAMA4
LYAR
MPHOSPH6
NACA
NFYA
PAFAH1B3
PEX14
PIAS4
PIGC
PNP
PRPF40A
PSMD11
SAT1
SERPINB9
SUMO2
TAL1
TALDO1
TARDBP
TERF1
TNFRSF10C
TOLLIP
TP53
UTP3
VIM
WDR33
ZHX2
ZHX3
ZMYND11
ZNF33B
ZYX
9 interactors:
APOA1
FAM101B
LRSAM1
RAP1A
SLC27A6
SRPK1
SRPK2
TNFSF10
ZHX1
Entrez ID
11244
8794
HPRD ID
10379
04681
Ensembl ID
ENSG00000165156
ENSG00000173535
Uniprot IDs
Q9UKY1
O14798
PDB IDs
2ECB
2GHF
2LY9
3NAR
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Regulation Of Apoptotic Process
Positive Regulation Of Cell Death
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Cell Death
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Viral Process
Regulation Of Mitochondrion Organization
Negative Regulation Of Biosynthetic Process
Apoptotic Process
RNA Metabolic Process
Programmed Cell Death
Cell Death
Death
Cellular Metabolic Process
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrion Organization
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Cell Cycle
Gene Expression
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Cellular Process
Transcription, DNA-templated
Negative Regulation Of Gene Expression
Cell Cycle
Negative Regulation Of RNA Biosynthetic Process
RNA Biosynthetic Process
Rhythmic Process
Negative Regulation Of Cell Cycle
Developmental Process
Positive Regulation Of Protein Metabolic Process
Biosynthetic Process
Positive Regulation Of Protein Catabolic Process
Cell Cycle Process
Regulation Of Cell Cycle Process
Regulation Of Proteolysis
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Nitrogen Compound Metabolic Process
Cellular Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Viral Genome Replication
Negative Regulation Of Viral Genome Replication
Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of Viral Genome Replication
Positive Regulation Of Viral Process
Negative Regulation Of Transport
Negative Regulation Of Viral Process
Negative Regulation Of Cell Adhesion Molecule Production
Nuclear Speck Organization
Ubiquitin-dependent Endocytosis
Regulation Of MRNA Processing
Cell Differentiation
Regulation Of RNA Splicing
Negative Regulation Of Interleukin-1 Beta Secretion
Developmental Process
Nucleus Organization
Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling
Cholesterol Import
Negative Regulation Of Interleukin-1 Secretion
Regulation Of Viral Process
Negative Regulation Of Secretion By Cell
Negative Regulation Of Secretion
High-density Lipoprotein Particle Clearance
Platelet Activation
Protein Oxidation
Positive Regulation Of Intracellular Signal Transduction
Negative Regulation Of Heterotypic Cell-cell Adhesion
Negative Regulation Of Cytokine Secretion Involved In Immune Response
High-density Lipoprotein Particle Assembly
Cell Development
Positive Regulation Of Triglyceride Catabolic Process
Positive Regulation Of Cholesterol Esterification
Sperm Chromatin Condensation
Viral Budding
Regulation Of Intestinal Cholesterol Absorption
Rap Protein Signal Transduction
Phospholipid Homeostasis
Peptidyl-methionine Modification
Anatomical Structure Development
Regulation Of Cellular Component Organization
Regulation Of Cholesterol Esterification
Peripheral Nervous System Axon Regeneration
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Vasculogenesis
Phospholipid Efflux
Nerve Growth Factor Signaling Pathway
Regulation Of Cytokine Secretion Involved In Immune Response
Lipid Transport
Positive Regulation Of Fatty Acid Biosynthetic Process
Positive Regulation Of Lipoprotein Lipase Activity
Tagcloud
?
199a
3p
accumulating
bound
carcinogenesis
direct
dramatically
epigenetic
fingers
gastric
gc
homeoboxes
inversely
involve
micrornas
mir
mirnas
n87
nci
oncogenic
regulator
regulators
restoring
sgc
suppressed
untranslated
upregulated
utr
zinc
Tagcloud (Difference)
?
199a
3p
accumulating
bound
carcinogenesis
direct
dramatically
epigenetic
fingers
gastric
gc
homeoboxes
inversely
involve
micrornas
mir
mirnas
n87
nci
oncogenic
regulator
regulators
restoring
sgc
suppressed
untranslated
upregulated
utr
zinc
Tagcloud (Intersection)
?