GET1 and APOL2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		GET1	APOL2
Name		guided entry of tail-anchored proteins factor 1	apolipoprotein L2
Structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex	Extracellular Region Cytoplasm Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Protein-membrane Adaptor Activity	Signaling Receptor Binding Protein Binding High-density Lipoprotein Particle Binding Lipid Binding
	Biological Process	Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Sensory Perception Of Sound Protein Insertion Into ER Membrane Synapse Organization Protein Stabilization Establishment Of Localization In Cell Otic Vesicle Development Tail-anchored Membrane Protein Insertion Into ER Membrane Establishment Of Protein Localization To Membrane	Lipid Metabolic Process Lipid Transport Acute-phase Response Cholesterol Metabolic Process Lipoprotein Metabolic Process Maternal Process Involved In Female Pregnancy
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	None
GWAS		No GWAS studies recorded	Epigenetic age acceleration in alcohol use disorder ( 31466081 )
Novel Interactors		6 novel interactors: BOC GATD3 PDXK SCN3A SLC4A2 TRAPPC10	None recorded
Interacting Genes		28 interacting genes: ABHD5 APOA2 APOL2 AQP1 CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 HMOX2 HTATIP2 ORMDL3 PLPP4 PTPN9 RASGRP3 RTP2 SERP2 SLC35E3 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42	38 interacting genes: AIG1 APOC2 APOC4 AR BSND CISD2 CYBC1 EBAG9 ELOVL4 EMP1 ERGIC3 FAM209A FAM210B GET1 GJB5 ITGB2 KCNA1 LMNA MARCHF3 MFF MGST3 PANX1 PSCA SFXN5 SIT1 SLC18A1 SLC26A6 SLC35H1 STX1A STX2 TIMMDC1 TMED8 TMEM139 TMEM45B TMEM52B TMEM60 USE1 YIPF6
Entrez ID		7485	23780
HPRD ID		04224	06263
Ensembl ID		ENSG00000182093	ENSG00000128335
Uniprot IDs		O00258	Q9BQE5
PDB IDs		6SO5 8CQZ 8CR1 8CR2	7LF8
GO Terms Enriched among Interactors		Basolateral Plasma Membrane Membrane Serine Palmitoyltransferase Complex	Membrane SNAP Receptor Activity Endoplasmic Reticulum SNARE Complex