APOL2 and CYBC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		APOL2	CYBC1
Description		apolipoprotein L2	cytochrome b-245 chaperone 1
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Endoplasmic Reticulum Membrane Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding High-density Lipoprotein Particle Binding Lipid Binding	Protein Binding
	Biological Process	Lipid Metabolic Process Lipid Transport Acute-phase Response Cholesterol Metabolic Process Lipoprotein Metabolic Process Maternal Process Involved In Female Pregnancy	Immune System Process Innate Immune Response Respiratory Burst After Phagocytosis
Pathways
Drugs
Diseases
GWAS		Epigenetic age acceleration in alcohol use disorder ( 31466081)
Interacting Genes		38 interacting genes: AIG1 APOC2 APOC4 AR BSND CISD2 CYBC1 EBAG9 ELOVL4 EMP1 ERGIC3 FAM209A FAM210B GET1 GJB5 ITGB2 KCNA1 LMNA MARCHF3 MFF MGST3 PANX1 PSCA SFXN5 SIT1 SLC18A1 SLC26A6 SLC35H1 STX1A STX2 TIMMDC1 TMED8 TMEM139 TMEM45B TMEM52B TMEM60 USE1 YIPF6	65 interacting genes: ADIPOQ AGTRAP AHNAK2 AIG1 APCDD1L APOA2 APOL2 AQP10 AQP6 AQP8 ARLN BET1 C14orf180 CD53 CISD2 CLDN7 CLN6 COQ9 CPLX4 CREB3 CREB3L1 CYBB ERGIC3 ETS1 FAM209A GJA8 GPR151 GPR152 GPX8 HSD17B11 HSD17B13 INSIG2 JAGN1 KASH5 KIR2DL3 LAT LMNA LXN MFF MGST3 MTIF3 NINJ2 NOX3 NRM P2RX1 PDZK1IP1 PEX12 PLIN3 PLP1 PLP2 SCD SHISA4 SLC35H1 SLC71A2 SPN SSMEM1 STX2 THBD TM4SF19 TMEM128 TMEM80 TMPRSS2 TMX2 TRAM1L1 TSPAN12
Entrez ID		23780	79415
HPRD ID		06263	14630
Ensembl ID		ENSG00000128335	ENSG00000178927
Uniprot IDs		Q9BQE5	Q9BQA9
PDB IDs		7LF8	8KEI
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity Endoplasmic Reticulum SNARE Complex	Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Water Channel Activity Channel Activity Negative Regulation Of Cholesterol Import Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On NAD(P)H, Oxygen As Acceptor Regulation Of Cholesterol Import One-carbon Compound Transport Water Transport Superoxide-generating NADPH Oxidase Activity Identical Protein Binding Fluid Transport Lipid Droplet Ammonium Channel Activity Urea Transmembrane Transport
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