GET1 and COX20

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		GET1	COX20
Name		guided entry of tail-anchored proteins factor 1	cytochrome c oxidase assembly factor COX20
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Protein Binding Protein-membrane Adaptor Activity	Protein Binding
	Biological Process	Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Sensory Perception Of Sound Protein Insertion Into ER Membrane Synapse Organization Protein Stabilization Establishment Of Localization In Cell Otic Vesicle Development Tail-anchored Membrane Protein Insertion Into ER Membrane Establishment Of Protein Localization To Membrane	Mitochondrial Cytochrome C Oxidase Assembly
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Complex IV assembly
GWAS		No GWAS studies recorded	No GWAS studies recorded
Novel Interactors		6 novel interactors: BOC GATD3 PDXK SCN3A SLC4A2 TRAPPC10	None recorded
Interacting Genes		28 interacting genes: ABHD5 APOA2 APOL2 AQP1 CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 HMOX2 HTATIP2 ORMDL3 PLPP4 PTPN9 RASGRP3 RTP2 SERP2 SLC35E3 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42	22 interacting genes: AQP6 C1orf56 CHIA CREB3L1 DYNC1H1 ERGIC3 FCER1G FUNDC2 GET1 GJA8 GOLT1A JAGN1 MAOB NCBP2AS2 PGRMC2 SLC10A1 SLC10A6 TCEA2 TEX44 TMEM31 TMEM35A TMX2
Entrez ID		7485	116228
HPRD ID		04224	13307
Ensembl ID		ENSG00000182093	ENSG00000203667
Uniprot IDs		O00258	B3KM21 Q5RI15
PDB IDs		6SO5 8CQZ 8CR1 8CR2	Not available
GO Terms Enriched among Interactors		Basolateral Plasma Membrane Membrane Serine Palmitoyltransferase Complex	Bile Acid:sodium Symporter Activity