GET1 and CAMLG

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (affinity chromatography technology, two hybrid)

		GET1	CAMLG
Name		guided entry of tail-anchored proteins factor 1	calcium modulating ligand
Structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex
	Molecular Function	Protein Binding Protein-membrane Adaptor Activity	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Sensory Perception Of Sound Protein Insertion Into ER Membrane Synapse Organization Protein Stabilization Establishment Of Localization In Cell Otic Vesicle Development Tail-anchored Membrane Protein Insertion Into ER Membrane Establishment Of Protein Localization To Membrane	B Cell Homeostasis Receptor Recycling Defense Response Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Insertion Into ER Membrane Protein Stabilization Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		None	Cyclosporine Voclosporin
GWAS		No GWAS studies recorded	Height ( 18391951 )
Novel Interactors		6 novel interactors: BOC GATD3 PDXK SCN3A SLC4A2 TRAPPC10	1 novel interactors: STT3B
Interacting Genes		28 interacting genes: ABHD5 APOA2 APOL2 AQP1 CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 HMOX2 HTATIP2 ORMDL3 PLPP4 PTPN9 RASGRP3 RTP2 SERP2 SLC35E3 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42	21 interacting genes: ADIPOQ AGR2 BCL2L13 EGFR ETNK1 F11R GET1 HSP90B1 HSPA13 KCNE4 LAT LCN2 OCIAD1 PBXIP1 PGRMC1 PKHD1 PPIB TMEM31 TNFRSF13B TXNDC12 VWC2
Entrez ID		7485	819
HPRD ID		04224	03073
Ensembl ID		ENSG00000182093	ENSG00000164615
Uniprot IDs		O00258	P49069
PDB IDs		6SO5 8CQZ 8CR1 8CR2	6SO5 8CR1
GO Terms Enriched among Interactors		Basolateral Plasma Membrane Membrane Serine Palmitoyltransferase Complex	Endoplasmic Reticulum Localization Within Membrane Positive Regulation Of Protein Localization To Plasma Membrane Endoplasmic Reticulum Chaperone Complex Positive Regulation Of Protein Localization To Cell Periphery Positive Regulation Of Protein Localization To Membrane Protein Localization To Cell Periphery Digestive Tract Morphogenesis Protein-containing Complex Smooth Endoplasmic Reticulum Regulation Of Protein Localization To Plasma Membrane Regulation Of Cellular Localization Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Protein Localization To Membrane