GET1 and SLC35E3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GET1	SLC35E3
Description		guided entry of tail-anchored proteins factor 1	solute carrier family 35 member E3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex	Golgi Apparatus Membrane
	Molecular Function	Protein Binding Protein-membrane Adaptor Activity	Nucleotide-sugar Transmembrane Transporter Activity Protein Binding Antiporter Activity
	Biological Process	Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Sensory Perception Of Sound Protein Insertion Into ER Membrane Synapse Organization Protein Stabilization Establishment Of Localization In Cell Otic Vesicle Development Tail-anchored Membrane Protein Insertion Into ER Membrane Establishment Of Protein Localization To Membrane	Organophosphate Ester Transport Nucleobase-containing Compound Transport Transmembrane Transport Carbohydrate Derivative Transport
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS			Mean reticulocyte volume ( 32888494) White blood cell count ( 20139978)
Interacting Genes		28 interacting genes: ABHD5 APOA2 APOL2 AQP1 CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 HMOX2 HTATIP2 ORMDL3 PLPP4 PTPN9 RASGRP3 RTP2 SERP2 SLC35E3 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42	23 interacting genes: ADIPOQ ARLN ATP6V0C BCL2L2 BIK BNIP2 CSGALNACT2 FAM209A FFAR2 FXYD6 GET1 GPR25 LNPEP PLP1 RUSF1 SELENOK SLC66A2 SPG21 SSMEM1 TMEM14B TMEM234 TMEM60 TTPA
Entrez ID		7485	55508
HPRD ID		04224	15375
Ensembl ID		ENSG00000182093	ENSG00000175782
Uniprot IDs		O00258	Q7Z769
PDB IDs		6SO5 8CQZ 8CR1 8CR2
Enriched GO Terms of Interacting Partners?		Basolateral Plasma Membrane Membrane Serine Palmitoyltransferase Complex	Membrane Bcl-2 Family Protein Complex Positive Regulation Of Chemokine Production Positive Regulation Of Monocyte Chemotactic Protein-1 Production
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