APOL2 and PSCA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		APOL2	PSCA
Description		apolipoprotein L2	prostate stem cell antigen
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Endoplasmic Reticulum Membrane Membrane	Extracellular Region Plasma Membrane Membrane Synapse Extracellular Exosome Side Of Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding High-density Lipoprotein Particle Binding Lipid Binding	Acetylcholine Receptor Regulator Activity Acetylcholine Receptor Binding
	Biological Process	Lipid Metabolic Process Lipid Transport Acute-phase Response Cholesterol Metabolic Process Lipoprotein Metabolic Process Maternal Process Involved In Female Pregnancy	Negative Regulation Of ERK1 And ERK2 Cascade Acetylcholine Receptor Signaling Pathway Regulation Of Neurotransmitter Receptor Activity
Pathways			Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Epigenetic age acceleration in alcohol use disorder ( 31466081)	Bladder cancer ( 20972438 24163127 19648920 32117775) Blood urea nitrogen levels ( 31152163) Duodenal ulcer ( 22387998) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric atrophy ( 30753327) Gastric cancer ( 26098866 30189721) Non-cardia gastric cancer ( 26701879) Optic disc size ( 31809533) Pepsinogen I/II ratio ( 30753327) Schizophrenia ( 33169155) Severe gastric atrophy ( 30753327) Urinary tract infection frequency ( 28928442) Vertical cup-disc ratio ( 28073927)
Interacting Genes		38 interacting genes: AIG1 APOC2 APOC4 AR BSND CISD2 CYBC1 EBAG9 ELOVL4 EMP1 ERGIC3 FAM209A FAM210B GET1 GJB5 ITGB2 KCNA1 LMNA MARCHF3 MFF MGST3 PANX1 PSCA SFXN5 SIT1 SLC18A1 SLC26A6 SLC35H1 STX1A STX2 TIMMDC1 TMED8 TMEM139 TMEM45B TMEM52B TMEM60 USE1 YIPF6	43 interacting genes: AGPAT5 AIG1 APOA2 APOL2 BCL2L2 BRICD5 CATSPERH CD53 CDIPT CMTM5 CTSA CYB561D2 DERL3 ERG28 INSIG2 JAGN1 LAT MOSPD3 PLP2 PLPP4 RUSF1 SLC16A4 SLC30A8 SLC35A1 SLC7A1 SMIM3 ST6GAL2 STX8 SYS1 TMEM140 TMEM147 TMEM218 TMEM239 TMEM243 TMEM42 TMEM54 TMEM86B TMEM97 TRARG1 TSPO2 UNC93A VAMP4 YIPF6
Entrez ID		23780	8000
HPRD ID		06263	03919
Ensembl ID		ENSG00000128335	ENSG00000167653
Uniprot IDs		Q9BQE5	O43653
PDB IDs		7LF8
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity Endoplasmic Reticulum SNARE Complex	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Sterol Metabolic Process Cholesterol Binding High-density Lipoprotein Particle Binding Establishment Of Protein Localization To Plasma Membrane CDP-diacylglycerol Metabolic Process Endosome To Plasma Membrane Protein Transport Endomembrane System Oxysterol Binding Lipid Metabolic Process Acylglycerol Metabolic Process Neutral Lipid Metabolic Process Glycerolipid Metabolic Process Cellular Localization Protein Localization To Membrane Trans-Golgi Network Insulin Metabolic Process
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