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GET1

Name guided entry of tail-anchored proteins factor 1
Structure PDB 6SO5
Novel Interactors 6 novel interactors: BOC GATD3 PDXK SCN3A SLC4A2 TRAPPC10
Interactors 28 interactors: ABHD5 APOA2 APOL2 AQP1 CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 HMOX2 HTATIP2 ORMDL3 PLPP4 PTPN9 RASGRP3 RTP2 SERP2 SLC35E3 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42
GO Annotations Cellular Component
  • Nucleus
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Membrane
  • GET Complex
Molecular Function
  • Protein Binding
  • Protein-membrane Adaptor Activity
Biological Process
  • Post-translational Protein Targeting To Endoplasmic Reticulum Membrane
  • Sensory Perception Of Sound
  • Protein Insertion Into ER Membrane
  • Synapse Organization
  • Protein Stabilization
  • Establishment Of Localization In Cell
  • Otic Vesicle Development
  • Tail-anchored Membrane Protein Insertion Into ER Membrane
  • Establishment Of Protein Localization To Membrane
Pathways
  • Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
GWAS No GWAS studies recorded
Entrez ID 7485
HPRD ID 04224
Ensembl ID ENSG00000182093
Uniprot IDs O00258
PDB IDs 6SO5 8CQZ 8CR1 8CR2
GO Terms Enriched among Interactors ?
  • Basolateral Plasma Membrane
  • Membrane
  • Serine Palmitoyltransferase Complex

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