GET1 and TRAPPC10

		GET1	TRAPPC10
Description		guided entry of tail-anchored proteins factor 1	trafficking protein particle complex subunit 10
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex	Cytoplasm Golgi Apparatus Cytosol TRAPP Complex TRAPPII Protein Complex
	Molecular Function	Protein Binding Protein-membrane Adaptor Activity	Protein Binding
	Biological Process	Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Sensory Perception Of Sound Protein Insertion Into ER Membrane Synapse Organization Protein Stabilization Establishment Of Localization In Cell Otic Vesicle Development Tail-anchored Membrane Protein Insertion Into ER Membrane Establishment Of Protein Localization To Membrane	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Vesicle Coating Vesicle-mediated Transport Early Endosome To Golgi Transport Golgi Vesicle Transport Vesicle Tethering
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS
Interacting Genes		28 interacting genes: ABHD5 APOA2 APOL2 AQP1 CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 HMOX2 HTATIP2 ORMDL3 PLPP4 PTPN9 RASGRP3 RTP2 SERP2 SLC35E3 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42	5 interacting genes: TRAPPC12 TRAPPC3L TRAPPC6A TRAPPC6B TRAPPC8
Entrez ID		7485	7109
HPRD ID		04224	03656
Ensembl ID		ENSG00000182093	ENSG00000160218
Uniprot IDs		O00258	P48553
PDB IDs		6SO5 8CQZ 8CR1 8CR2
Enriched GO Terms of Interacting Partners?		Basolateral Plasma Membrane Membrane Serine Palmitoyltransferase Complex	TRAPP Complex Vesicle Tethering Vesicle Coating Endoplasmic Reticulum To Golgi Vesicle-mediated Transport TRAPPIII Protein Complex Maintenance Of Gastrointestinal Epithelium COPII Vesicle Coating Golgi Vesicle Transport Epithelial Structure Maintenance Digestive System Process Vesicle Organization Anatomical Structure Homeostasis Tissue Homeostasis Methotrexate Transport Methotrexate Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Multicellular Organismal-level Homeostasis CXCR4 Chemokine Receptor Binding Mono-ADP-D-ribose Binding Cis-Golgi Network Cellular Localization Establishment Of Localization In Cell Folate Import Across Plasma Membrane 2',3'-cyclic GMP-AMP Binding Cyclic-GMP-AMP Transmembrane Transporter Activity Cellular Response To Temperature Stimulus Positive Regulation Of Protein Localization To Kinetochore Folic Acid Transmembrane Transporter Activity Folate Transmembrane Transport Entry Receptor-mediated Virion Attachment To Host Cell GET Complex Vesicle-mediated Transport Intracellular Transport Regulation Of Kinetochore Assembly Negative Regulation Of Gastric Acid Secretion Viral Translation ADP-ribose Diphosphatase Activity
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