APOL2 and SFXN5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		APOL2	SFXN5
Description		apolipoprotein L2	sideroflexin 5
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Endoplasmic Reticulum Membrane Membrane	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding High-density Lipoprotein Particle Binding Lipid Binding	Protein Binding Monoatomic Ion Transmembrane Transporter Activity Citrate Transmembrane Transporter Activity
	Biological Process	Lipid Metabolic Process Lipid Transport Acute-phase Response Cholesterol Metabolic Process Lipoprotein Metabolic Process Maternal Process Involved In Female Pregnancy	Monoatomic Ion Transport Amino Acid Transport Citrate Transport Monoatomic Ion Transmembrane Transport Transmembrane Transport Positive Regulation Of Cold-induced Thermogenesis Mitochondrial Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Epigenetic age acceleration in alcohol use disorder ( 31466081)	Breast milk fatty acid composition (maternal genotype effect) ( 29514873) Malaria ( 31844061) Non-word reading ( 30741946) Schizophrenia ( 30285260)
Interacting Genes		38 interacting genes: AIG1 APOC2 APOC4 AR BSND CISD2 CYBC1 EBAG9 ELOVL4 EMP1 ERGIC3 FAM209A FAM210B GET1 GJB5 ITGB2 KCNA1 LMNA MARCHF3 MFF MGST3 PANX1 PSCA SFXN5 SIT1 SLC18A1 SLC26A6 SLC35H1 STX1A STX2 TIMMDC1 TMED8 TMEM139 TMEM45B TMEM52B TMEM60 USE1 YIPF6	9 interacting genes: APOL2 AQP6 CREB3L1 EBP ERGIC3 STOM TMEM237 TMEM86B TMPPE
Entrez ID		23780	94097
HPRD ID		06263	18047
Ensembl ID		ENSG00000128335	ENSG00000144040
Uniprot IDs		Q9BQE5	B4DIJ8 B8ZZJ6 Q8TD22
PDB IDs		7LF8
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity Endoplasmic Reticulum SNARE Complex	PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Membrane Endoplasmic Reticulum C-8 Sterol Isomerase Activity Endoplasmic Reticulum Membrane Cholesterol-5,6-oxide Hydrolase Activity Cholestenol Delta-isomerase Activity Retrograde Transporter Complex, Golgi To ER D-lysine 5,6-aminomutase Activity Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol Cholesterol Metabolic Process Steroid Delta-isomerase Activity Extracellular Matrix Constituent Secretion Sterol Metabolic Process Transporter Complex Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Cone Photoreceptor Outer Segment Monoatomic Anion Channel Activity Renal Water Transport Ammonium Channel Activity Ossification Involved In Bone Maturation Rod Photoreceptor Outer Segment
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