APOL2 and SLC26A6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		APOL2	SLC26A6
Description		apolipoprotein L2	solute carrier family 26 member 6
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Endoplasmic Reticulum Membrane Membrane	Endoplasmic Reticulum Cytosol Plasma Membrane Vesicle Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Brush Border Membrane Vesicle Chloride Channel Complex Sperm Midpiece
	Molecular Function	Signaling Receptor Binding Protein Binding High-density Lipoprotein Particle Binding Lipid Binding	Chloride Channel Activity Solute:inorganic Anion Antiporter Activity Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Bicarbonate Transmembrane Transporter Activity Chloride Transmembrane Transporter Activity Sulfate Transmembrane Transporter Activity Antiporter Activity Sulfate:bicarbonate Antiporter Activity Formate Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity Transferase Activity Oxalate Transmembrane Transporter Activity PDZ Domain Binding Identical Protein Binding Chloride:bicarbonate Antiporter Activity
	Biological Process	Lipid Metabolic Process Lipid Transport Acute-phase Response Cholesterol Metabolic Process Lipoprotein Metabolic Process Maternal Process Involved In Female Pregnancy	Monoatomic Ion Transport Chloride Transport Bicarbonate Transport Formate Transport Mannitol Transmembrane Transport Oxalate Transport Transepithelial Chloride Transport Monoatomic Ion Transmembrane Transport Angiotensin-activated Signaling Pathway Epithelial Fluid Transport Estrous Cycle Oxalic Acid Secretion Sperm Capacitation Intestinal Absorption Regulation Of Intracellular PH Intracellular PH Elevation Establishment Of Localization In Cell Transmembrane Transport Protein Kinase C Signaling Transepithelial Transport Cellular Response To CAMP Cellular Response To Fructose Stimulus Cellular Response To Type II Interferon Sulfate Transmembrane Transport Chloride Transmembrane Transport Positive Regulation Of Dipeptide Transmembrane Transport
Pathways			Inorganic anion exchange by SLC26 transporters
Drugs
Diseases
GWAS		Epigenetic age acceleration in alcohol use disorder ( 31466081)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		38 interacting genes: AIG1 APOC2 APOC4 AR BSND CISD2 CYBC1 EBAG9 ELOVL4 EMP1 ERGIC3 FAM209A FAM210B GET1 GJB5 ITGB2 KCNA1 LMNA MARCHF3 MFF MGST3 PANX1 PSCA SFXN5 SIT1 SLC18A1 SLC26A6 SLC35H1 STX1A STX2 TIMMDC1 TMED8 TMEM139 TMEM45B TMEM52B TMEM60 USE1 YIPF6	12 interacting genes: APOL2 AQP2 BET1 CD81 ERG28 LAT PDZK1 PLP1 SNORC TF TMEM128 TMEM201
Entrez ID		23780	65010
HPRD ID		06263	10235
Ensembl ID		ENSG00000128335	ENSG00000225697
Uniprot IDs		Q9BQE5	A0A0C4DFT5 G3XAC1 Q96MZ1 Q9BXS9
PDB IDs		7LF8	8OPQ
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity Endoplasmic Reticulum SNARE Complex	Membrane Transferrin Receptor Binding
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