APOL2 and BSND

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		APOL2	BSND
Name		apolipoprotein L2	barttin CLCNK type accessory subunit beta
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Endoplasmic Reticulum Membrane Membrane	Plasma Membrane Membrane Basolateral Plasma Membrane Protein-containing Complex
	Molecular Function	Signaling Receptor Binding Protein Binding High-density Lipoprotein Particle Binding Lipid Binding	Chloride Channel Activity Protein Binding Chloride Channel Regulator Activity
	Biological Process	Lipid Metabolic Process Lipid Transport Acute-phase Response Cholesterol Metabolic Process Lipoprotein Metabolic Process Maternal Process Involved In Female Pregnancy	Chloride Transport Sensory Perception Of Sound Chloride Transmembrane Transport
Pathways		None	Stimuli-sensing channels
Diseases		None	Bartter syndrome
GWAS		Epigenetic age acceleration in alcohol use disorder ( 31466081 )	Allergic rhinitis ( 25085501 ) Carotid intima media thickness x smoking interaction ( 32117412 ) Coronary artery disease ( 32469254 33020668 ) Medication use (HMG CoA reductase inhibitors) ( 31015401 ) Mitochondrial DNA copy number ( 30704525 )
Interacting Genes		38 interacting genes: AIG1 APOC2 APOC4 AR BSND CISD2 CYBC1 EBAG9 ELOVL4 EMP1 ERGIC3 FAM209A FAM210B GET1 GJB5 ITGB2 KCNA1 LMNA MARCHF3 MFF MGST3 PANX1 PSCA SFXN5 SIT1 SLC18A1 SLC26A6 SLC35H1 STX1A STX2 TIMMDC1 TMED8 TMEM139 TMEM45B TMEM52B TMEM60 USE1 YIPF6	28 interacting genes: ADIPOQ APOL2 APP ARFIP1 BMP10 CDIPT CERT1 COL4A5 COL8A2 CSGALNACT2 CTSA ECPAS FATE1 GAD2 IGFBP5 JAGN1 MYG1 PBX3 PLSCR2 PTPN9 SLC30A8 SPG21 STX8 TBRG4 THAP4 TMEM60 VAMP3 ZFPL1
Entrez ID		23780	7809
HPRD ID		06263	05914
Ensembl ID		ENSG00000128335	ENSG00000162399
Uniprot IDs		Q9BQE5	Q5VU50 Q8WZ55
PDB IDs		7LF8	Not available
GO Terms Enriched among Interactors		Membrane SNAP Receptor Activity Endoplasmic Reticulum SNARE Complex	Amyloid-beta Complex Lipoprotein Metabolic Process Response To Purine-containing Compound Growth Cone Lamellipodium Collateral Sprouting Regulation Of Response To Calcium Ion Regulation Of Establishment Of Protein Localization Recycling Endosome Trans-Golgi Network Membrane Amylin Binding Neuron Maturation Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Response To Cytokine Regulation Of Protein Localization Regulation Of Protein Transport Endoplasmic Reticulum Locomotory Behavior Response To CAMP Golgi Apparatus Endoplasmic Reticulum Lumen Positive Regulation Of CAMP/PKA Signal Transduction Extracellular Matrix Structural Constituent Conferring Tensile Strength Collagen Trimer Extracellular Matrix Structural Constituent Negative Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Skeletal Muscle Hypertrophy Posterior Compartment Specification Anterior Compartment Pattern Formation Regulation Of Cellular Localization Mitochondrial MRNA Processing Regulation Of Hormone Secretion Response To Type II Interferon SNAP Receptor Activity Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Response To Glucose Positive Regulation Of Glycogen (starch) Synthase Activity Response To Monosaccharide Phosphatidylinositol-4-phosphate Binding Amide Transport Intermembrane Sphingolipid Transfer CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Negative Regulation Of Retrograde Transport, Endosome To Golgi Peroxynitrite Isomerase Activity Insulin Metabolic Process Early Endosome Negative Regulation Of Secretion By Cell Regulation Of System Process