GET1 and HTATIP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GET1	HTATIP2
Description		guided entry of tail-anchored proteins factor 1	HIV-1 Tat interactive protein 2
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GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex	Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Protein-membrane Adaptor Activity	Catalytic Activity Protein Serine/threonine Kinase Activity Protein Binding
	Biological Process	Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Sensory Perception Of Sound Protein Insertion Into ER Membrane Synapse Organization Protein Stabilization Establishment Of Localization In Cell Otic Vesicle Development Tail-anchored Membrane Protein Insertion Into ER Membrane Establishment Of Protein Localization To Membrane	Regulation Of Translation Positive Regulation Of Programmed Cell Death Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs			Polyethylene glycol 400
Diseases
GWAS			Bell's palsy ( 33602968) Fractional shortening ( 29403010) Obesity-related traits ( 23251661) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		28 interacting genes: ABHD5 APOA2 APOL2 AQP1 CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 HMOX2 HTATIP2 ORMDL3 PLPP4 PTPN9 RASGRP3 RTP2 SERP2 SLC35E3 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42	29 interacting genes: ABHD4 ACSL4 AQP6 ASF1A CD79A CFTR EHHADH ETS1 FAM209A FITM2 FKBP7 GET1 HDAC6 HSD17B11 JAGN1 JPH1 MIEF1 MTIF3 NCOA5 PITPNC1 PLIN2 RAB5A REEP4 RETREG3 SH3GLB1 SLC10A6 SLC18A1 TMEM115 TMX2
Entrez ID		7485	10553
HPRD ID		04224	09288
Ensembl ID		ENSG00000182093	ENSG00000109854
Uniprot IDs		O00258	Q9BUP3
PDB IDs		6SO5 8CQZ 8CR1 8CR2	2BKA
Enriched GO Terms of Interacting Partners?		Basolateral Plasma Membrane Membrane Serine Palmitoyltransferase Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Lipid Biosynthetic Process Lysophosphatidic Acid Acyltransferase Activity Endoplasmic Reticulum Organization Regulation Of Establishment Of Protein Localization Organelle Disassembly Fatty Acid Derivative Metabolic Process Alpha-linolenic Acid Metabolic Process
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