GET1 and TM4SF19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)

		GET1	TM4SF19
Description		guided entry of tail-anchored proteins factor 1	transmembrane 4 L six family member 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex	Cytoplasm Lysosome Lysosomal Membrane Cytoskeleton Actin Cytoskeleton Membrane Filopodium Cell Projection
	Molecular Function	Protein Binding Protein-membrane Adaptor Activity	Protein Binding Protein Homodimerization Activity
	Biological Process	Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Sensory Perception Of Sound Protein Insertion Into ER Membrane Synapse Organization Protein Stabilization Establishment Of Localization In Cell Otic Vesicle Development Tail-anchored Membrane Protein Insertion Into ER Membrane Establishment Of Protein Localization To Membrane	Positive Regulation Of Osteoclast Differentiation
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS
Interacting Genes		28 interacting genes: ABHD5 APOA2 APOL2 AQP1 CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 HMOX2 HTATIP2 ORMDL3 PLPP4 PTPN9 RASGRP3 RTP2 SERP2 SLC35E3 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42	39 interacting genes: ABHD16A ARLN ATP6V0B BNIP1 C14orf180 CCDC167 CD79A CRK CTXN3 CYBC1 CYP4F2 DAPP1 ERG28 GET1 GIMAP1 GIMAP5 GOSR2 GPR152 HMOX1 NDUFA3 PLP2 PMP22 RIN3 SEC22B SERP2 SMIM1 STAT3 STX7 SYS1 TMEM167B TMEM179B TMEM237 TMEM42 TNS2 TSNARE1 UBE2J1 VAMP3 VAMP4 ZFPL1
Entrez ID		7485	116211
HPRD ID		04224	14013
Ensembl ID		ENSG00000182093	ENSG00000145107
Uniprot IDs		O00258	B7ZW46 Q96DZ7
PDB IDs		6SO5 8CQZ 8CR1 8CR2
Enriched GO Terms of Interacting Partners?		Basolateral Plasma Membrane Membrane Serine Palmitoyltransferase Complex	Membrane SNAP Receptor Activity SNARE Complex Endoplasmic Reticulum Membrane Organelle Fusion Membrane Fusion Organelle Membrane Fusion Endoplasmic Reticulum Vesicle-mediated Transport Golgi Vesicle Transport Vesicle Fusion Golgi To Plasma Membrane Protein Transport Transport Vesicle Establishment Of Protein Localization To Plasma Membrane Vesicle Docking SNARE Complex Assembly Golgi To Plasma Membrane Transport SNARE Binding Golgi Membrane Endocytic Vesicle Membrane Organization Vesicle Organization Organelle Localization By Membrane Tethering Phagocytic Vesicle Membrane Protein Binding Membrane Docking
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