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TPI1 and UCHL5
Number of citations of the paper that reports this interaction (PMID
21800051
)
0
Data Source:
BioGRID
(pull down)
TPI1
UCHL5
Gene Name
triosephosphate isomerase 1
ubiquitin carboxyl-terminal hydrolase L5
Image
Gene Ontology Annotations
Cellular Component
Extracellular Space
Nucleus
Cytosol
Extracellular Vesicular Exosome
Proteasome Complex
Nucleus
Cytosol
Ino80 Complex
Molecular Function
Triose-phosphate Isomerase Activity
Protein Binding
Ubiquitin-specific Protease Activity
Endopeptidase Inhibitor Activity
Protein Binding
Omega Peptidase Activity
Poly(A) RNA Binding
Proteasome Binding
Biological Process
Carbohydrate Metabolic Process
Glucose Metabolic Process
Gluconeogenesis
Glycolytic Process
Pentose-phosphate Shunt
Multicellular Organismal Development
Pathogenesis
Glyceraldehyde-3-phosphate Metabolic Process
Small Molecule Metabolic Process
DNA Repair
DNA Recombination
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Ubiquitin-dependent Protein Catabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Endopeptidase Activity
Protein Deubiquitination
Lateral Ventricle Development
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Midbrain Development
Forebrain Morphogenesis
Regulation Of Proteasomal Protein Catabolic Process
Pathways
Gluconeogenesis
Glucose metabolism
Myoclonic epilepsy of Lafora
Glycogen storage diseases
Glycolysis
Metabolism of carbohydrates
Loss of Function of TGFBR2 in Cancer
TGFBR2 MSI Frameshift Mutants in Cancer
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Loss of Function of SMAD2/3 in Cancer
TGFBR2 Kinase Domain Mutants in Cancer
Loss of Function of SMAD4 in Cancer
Downregulation of TGF-beta receptor signaling
SMAD2/3 MH2 Domain Mutants in Cancer
TGFBR1 KD Mutants in Cancer
TGF-beta receptor signaling activates SMADs
TGFBR1 LBD Mutants in Cancer
Loss of Function of TGFBR1 in Cancer
Signaling by TGF-beta Receptor Complex
Signaling by TGF-beta Receptor Complex in Cancer
SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS
Cannabis dependence (
21668797
)
Protein-Protein Interactions
15 interactors:
APP
CCL11
CDKN2A
CFL1
DDX24
EGFR
LIPT1
MAPK6
PCNA
POT1
SETDB1
SP1
TERF1
UCHL5
YWHAQ
96 interactors:
ACTN4
ADRM1
ANP32B
ANP32E
ANXA1
ANXA4
ANXA7
ANXA8
APP
ARG1
ASPRV1
CALM1
CAP1
CAPZA1
CASP14
CDSN
CFL1
CSTA
DSC1
DSC3
DSP
DUSP14
EEF1G
EEF2
EIF4A1
EPPK1
FLG
GSTM3
HAUS7
HBA1
HBA2
HBB
HIST1H4A
HIST1H4B
HIST1H4C
HIST1H4D
HIST1H4E
HIST1H4F
HIST1H4H
HIST1H4I
HIST1H4J
HIST1H4K
HIST1H4L
HIST2H4A
HIST2H4B
HIST4H4
HSPB1
IDE
IGHG1
IVL
KDM1A
KRT12
KRT19
KRT26
KRT28
KRT73
KRT78
KRT80
LMNA
NACA
NFRKB
PJA1
PKM
PKP1
PLA2G2A
PNP
POF1B
PRDX6
PSMD8
RAB7A
RBCK1
RFFL
S100A14
S100A16
S100A7
SERPINB12
SERPINB3
SERPINB5
SET
SMAD2
SMAD3
SMAD7
TGM3
TPI1
TRIM27
TRIM46
TRIM54
TRIM55
TRIM63
TUBA4A
TXN
TXN2
UBE3A
USP28
YWHAZ
ZBED1
Entrez ID
7167
51377
HPRD ID
01833
10293
Ensembl ID
ENSG00000111669
ENSG00000116750
Uniprot IDs
P60174
Q53HE2
Q9Y5K5
PDB IDs
1HTI
1WYI
2IAM
2IAN
2JK2
2VOM
4BR1
4E41
3A7S
3IHR
3RII
3RIS
3TB3
Enriched GO Terms of Interacting Partners
?
Telomere Maintenance Via Telomere Lengthening
Regulation Of DNA Replication
Positive Regulation Of Organelle Organization
Negative Regulation Of Telomere Maintenance Via Telomerase
Homeostatic Process
Telomere Maintenance
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Negative Regulation Of Telomerase Activity
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Organ Development
Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Hydrolase Activity
Positive Regulation Of Cell Cycle
Regulation Of Catalytic Activity
Cellular Protein Modification Process
Regulation Of Telomerase Activity
Mitotic Cell Cycle Process
Developmental Process
Cellular Metabolic Process
Regulation Of Telomere Maintenance
Mitotic Cell Cycle
Negative Regulation Of Catalytic Activity
RNA-dependent DNA Replication
Negative Regulation Of DNA Biosynthetic Process
Regulation Of Mitotic Cell Cycle
Positive Regulation Of DNA Metabolic Process
Cell Cycle
G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Cellular Metabolic Process
Morphogenesis Of An Epithelial Fold
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Protein Metabolic Process
Regulation Of Organelle Organization
Positive Regulation Of Catalytic Activity
Positive Regulation Of Cytoskeleton Organization
System Development
Chromosome Organization
Cell Cycle Process
Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Process
MAPK Cascade
Cellular Protein Metabolic Process
Regulation Of Cell Cycle Phase Transition
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of DNA Biosynthetic Process
Regulation Of Cell Cycle G2/M Phase Transition
Negative Regulation Of DNA Replication
Chemotaxis
Histone H4-K20 Demethylation
Negative Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Hematopoietic Progenitor Cell Differentiation
DNA Replication-dependent Nucleosome Assembly
Regulation Of Megakaryocyte Differentiation
DNA Methylation On Cytosine
Chromatin Silencing At RDNA
Regulation Of Hematopoietic Progenitor Cell Differentiation
Histone Exchange
Histone Lysine Demethylation
Histone Demethylation
Protein Demethylation
CENP-A Containing Nucleosome Assembly
Chromatin Silencing
DNA Replication-independent Nucleosome Assembly
Demethylation
Centromere Complex Assembly
ATP-dependent Chromatin Remodeling
Negative Regulation Of Gene Expression, Epigenetic
Gene Silencing
DNA Methylation
Nucleosome Organization
Nucleosome Assembly
Chromatin Assembly
Telomere Maintenance
Negative Regulation Of Myeloid Cell Differentiation
DNA Modification
Chromatin Assembly Or Disassembly
Protein-DNA Complex Assembly
Protein Complex Assembly
Regulation Of Gene Expression, Epigenetic
DNA Packaging
Cellular Component Assembly
Regulation Of Myeloid Cell Differentiation
DNA Conformation Change
Chromatin Remodeling
Negative Regulation Of Cellular Metabolic Process
Regulation Of Immune System Process
Cellular Macromolecular Complex Assembly
Negative Regulation Of Cell Differentiation
Mitotic Cell Cycle
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Immune System Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Histone Modification
Negative Regulation Of Gene Expression
Keratinocyte Differentiation
Cellular Protein Metabolic Process
Homeostatic Process
Tagcloud
?
achieve
anxa2
biomarkers
ccsnk2a1
considerably
cscs
dataset
depicting
deprived
differentiated
eif4e
eliminates
gapdh
glioma
hnrnpk
hprd
hsp90beta1
hspa8
hypoxic
ipa
micro
namely
nampt
pgk1
proteomic
reviews
u87
undifferentiated
vimentin
Tagcloud (Difference)
?
achieve
anxa2
biomarkers
ccsnk2a1
considerably
cscs
dataset
depicting
deprived
differentiated
eif4e
eliminates
gapdh
glioma
hnrnpk
hprd
hsp90beta1
hspa8
hypoxic
ipa
micro
namely
nampt
pgk1
proteomic
reviews
u87
undifferentiated
vimentin
Tagcloud (Intersection)
?