TPI1 and LIPT1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		TPI1	LIPT1
Gene Name		triosephosphate isomerase 1	lipoyltransferase 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Extracellular Vesicular Exosome	Mitochondrion
	Molecular Function	Triose-phosphate Isomerase Activity Protein Binding	Transferase Activity, Transferring Acyl Groups
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pentose-phosphate Shunt Multicellular Organismal Development Pathogenesis Glyceraldehyde-3-phosphate Metabolic Process Small Molecule Metabolic Process	Cellular Protein Modification Process Lipid Metabolic Process Protein Lipoylation
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs			Lipoic Acid
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		15 interactors: APP CCL11 CDKN2A CFL1 DDX24 EGFR LIPT1 MAPK6 PCNA POT1 SETDB1 SP1 TERF1 UCHL5 YWHAQ	2 interactors: APP TPI1
Entrez ID		7167	51601
HPRD ID		01833	17282
Ensembl ID		ENSG00000111669	ENSG00000144182
Uniprot IDs		P60174 Q53HE2	Q9Y234
PDB IDs		1HTI 1WYI 2IAM 2IAN 2JK2 2VOM 4BR1 4E41
Enriched GO Terms of Interacting Partners?		Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Replication Positive Regulation Of Organelle Organization Negative Regulation Of Telomere Maintenance Via Telomerase Homeostatic Process Telomere Maintenance Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Organ Development Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Hydrolase Activity Positive Regulation Of Cell Cycle Regulation Of Catalytic Activity Cellular Protein Modification Process Regulation Of Telomerase Activity Mitotic Cell Cycle Process Developmental Process Cellular Metabolic Process Regulation Of Telomere Maintenance Mitotic Cell Cycle Negative Regulation Of Catalytic Activity RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of DNA Metabolic Process Cell Cycle G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Morphogenesis Of An Epithelial Fold Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Organelle Organization Positive Regulation Of Catalytic Activity Positive Regulation Of Cytoskeleton Organization System Development Chromosome Organization Cell Cycle Process Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process MAPK Cascade Cellular Protein Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of DNA Biosynthetic Process Regulation Of Cell Cycle G2/M Phase Transition Negative Regulation Of DNA Replication Chemotaxis	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Glyceraldehyde-3-phosphate Metabolic Process Pentose-phosphate Shunt Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Glucose 6-phosphate Metabolic Process RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway NADP Metabolic Process Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Gluconeogenesis Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Hexose Biosynthetic Process Visual Behavior Neuron Death Platelet Degranulation Cellular Aldehyde Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Nicotinamide Nucleotide Metabolic Process Developmental Cell Growth Regulation Of Synapse Structure Or Activity
Tagcloud ?		achieve anxa2 biomarkers ccsnk2a1 considerably cscs dataset depicting deprived differentiated eif4e eliminates gapdh glioma hnrnpk hprd hsp90beta1 hspa8 hypoxic ipa micro namely nampt pgk1 proteomic reviews u87 undifferentiated vimentin
Tagcloud (Difference) ?		achieve anxa2 biomarkers ccsnk2a1 considerably cscs dataset depicting deprived differentiated eif4e eliminates gapdh glioma hnrnpk hprd hsp90beta1 hspa8 hypoxic ipa micro namely nampt pgk1 proteomic reviews u87 undifferentiated vimentin
Tagcloud (Intersection) ?