STAT1 and PIK3CA

  • Number of citations of the paper that reports this interaction (PMID 11438544)
  • 41
  • Data Source:
  • BioGRID (enzymatic study)

STAT1

PIK3CA

Gene Name signal transducer and activator of transcription 1, 91kDa phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 103 interactors: ACTN4 ADRA1B AKT1 ATF3 BMX BRCA1 CAMK2D CAMK2G CASP3 CASP7 CCR1 CCR5 CREBBP CSE1L CSF2RB CXCR4 DCTN1 DDB1 DOT1L DUSP3 E2F1 EGFR EIF1AD EIF2AK2 ELP2 EP300 ERBB2 FADD FANCC FGFR3 FGFR4 FLT1 FOS FYN GFAP GNB2L1 GTF2I HADH HLA-B HSF1 HSP90AB1 IFNAR2 IFNGR1 IL27RA IL2RB IL2RG IRF1 IRF2 IRF9 JAK1 JAK2 JUN KDR KIT KPNA1 KPNA6 LCK LMO2 LZTR1 MAPK14 MAVS MCM3 MCM5 MDK ND4L NMI NOMO1 NOMO2 OTUD4 PDGFRA PDGFRB PIAS1 PIK3CA POR PRKCD PRMT1 PRMT3 PTK2 PTPN11 PTPN2 RAC1 RELA RPS6KA5 RXRA SHANK1 SPTAN1 SPTBN1 SRC STAT2 STAT3 STAT5A STAT5B SUMO4 SYK TNFRSF1A TNFRSF1B TRADD TYK2 UBC UBE2I VDR XPO1 ZNF467 43 interactors: ADAP1 AMBP APLP2 APPL1 ATPIF1 ATR DDX5 DNAJB6 FASLG FTL GABRB1 GNAQ GRIN2B HRAS IL3 IRS2 IRS4 ITIH1 KRAS LCK MRAS NEDD9 NRAS PDE4D PDGFRB PIK3R1 PIK3R3 PRKCD RASD2 RASGRP3 RPS20 RPS6KB1 SGK1 SH3KBP1 SLC9A3R1 SLC9A3R2 SMAD2 SMAD3 SQSTM1 STAT1 TICAM1 UFD1L VARS2
Entrez ID 6772 5290
HPRD ID 02777 01382
Ensembl ID ENSG00000115415
Uniprot IDs J3KPM9 P42224 P42336
PDB IDs 1BF5 1YVL 2KA6 2ENQ 2RD0 3HHM 3HIZ 3ZIM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  myc  nmi  potentiate  recruitment  reveal  screen  stat2  stat5  stat5b  stats  yeast 
amplified  biomarker  e542k  e545d  e545k  embedded  fixed  formalin  h1047l  h1047r  homolog  metastatic  namely  next  oncogenic  paraffin  phospho  phosphoinositol  pi3k  pras40thr246  proline  pten  reflect  refractory  respond  retrospectively  tensin  trastuzumab  unlikely 
Tagcloud (Difference) ?
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  myc  nmi  potentiate  recruitment  reveal  screen  stat2  stat5  stat5b  stats  yeast 
amplified  biomarker  e542k  e545d  e545k  embedded  fixed  formalin  h1047l  h1047r  homolog  metastatic  namely  next  oncogenic  paraffin  phospho  phosphoinositol  pi3k  pras40thr246  proline  pten  reflect  refractory  respond  retrospectively  tensin  trastuzumab  unlikely 
Tagcloud (Intersection) ?