KLF10 and ZNF512B

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)

		KLF10	ZNF512B
Gene Name		Kruppel-like factor 10	zinc finger protein 512B
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	Core Promoter Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Metal Ion Binding	DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Transcription, DNA-templated Transforming Growth Factor Beta Receptor Signaling Pathway Cell-cell Signaling Circadian Rhythm Cell Proliferation Negative Regulation Of Cell Proliferation Cellular Response To Starvation Bone Mineralization Somatic Stem Cell Maintenance Regulation Of Circadian Rhythm Positive Regulation Of Osteoclast Differentiation Negative Regulation Of Transcription, DNA-templated Cellular Response To Peptide	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		13 interactors: BOP1 CDK6 CRIP2 KAT2B LENG1 LRRC75A-AS1 PIGC RPL14 SF3B3 SIN3A SP1 TNS1 ZNF512B	60 interactors: ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BRD1 BTBD2 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FAM129B FHL3 GLRX3 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MYH10 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2
Entrez ID		7071	57473
HPRD ID		03527	13840
Ensembl ID		ENSG00000155090	ENSG00000196700
Uniprot IDs		Q13118	Q96KM6
PDB IDs		2EPA	2GQJ
Enriched GO Terms of Interacting Partners?		Hematopoietic Progenitor Cell Differentiation Ribosomal Large Subunit Biogenesis Hemopoiesis Immune System Development RNA Metabolic Process Rhythmic Process Response To Methylglyoxal Sequestering Of Nodal From Receptor Via Nodal Binding Cell Dedifferentiation Negative Regulation Of Histone H3-K27 Acetylation Regulation Of Cell Cycle Histone H3-K9 Acetylation Regulation Of Protein ADP-ribosylation Negative Regulation Of Nodal Signaling Pathway Cleavage In ITS2 Between 5.8S RRNA And LSU-rRNA Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Chromatin Silencing RRNA Processing RRNA Metabolic Process Notch Signaling Pathway Viral Process Cell Cycle Arrest Determination Of Left/right Asymmetry In Lateral Mesoderm Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Nodal Signaling Pathway Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter Maturation Of LSU-rRNA Gene Expression Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter Sequestering Of Extracellular Ligand From Receptor Ribosome Biogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Negative Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Cellular Senescence Cellular Nitrogen Compound Metabolic Process Positive Regulation By Host Of Viral Transcription Fibroblast Migration Regulation Of Protein Glycosylation Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Embryonic Process Involved In Female Pregnancy DNA-templated Transcription, Initiation N-terminal Protein Amino Acid Acetylation Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)	Regulation Of Cellular Process Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organ Development System Development Transcription, DNA-templated Developmental Process Chromosome Organization Anatomical Structure Development Regulation Of Gene Expression RNA Biosynthetic Process Response To Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Biosynthetic Process Cell Cycle Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Cycle Process Multicellular Organismal Development Viral Genome Replication Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Organization Wnt Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cell Surface Receptor Signaling Pathway Organelle Organization Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Chromatin Remodeling RNA Metabolic Process Primary MiRNA Processing Vesicle-mediated Transport Endosomal Transport Regulation Of Signal Transduction Cellular Response To Stress Mitotic Cell Cycle Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Expression Response To Stress Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		acetyltransferase advance antagonistic associate characterize epigenetically foxp3 indeed inducibility inherited integrate integrated interacting kruppel modifying nh2 pcaf physically recapitulated reciprocal renders reporter repressor sin3 studying toggle underlie underlies works
Tagcloud (Difference) ?		acetyltransferase advance antagonistic associate characterize epigenetically foxp3 indeed inducibility inherited integrate integrated interacting kruppel modifying nh2 pcaf physically recapitulated reciprocal renders reporter repressor sin3 studying toggle underlie underlies works
Tagcloud (Intersection) ?