KLF10 and TNS1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		KLF10	TNS1
Description		KLF transcription factor 10	tensin 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytoplasm Cytoskeleton Focal Adhesion Cell Surface Cell-substrate Junction Anchoring Junction
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Actin Binding Phosphoprotein Phosphatase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell-cell Signaling Circadian Rhythm Negative Regulation Of Cell Population Proliferation Cellular Response To Starvation Bone Mineralization Somatic Stem Cell Population Maintenance Regulation Of Circadian Rhythm Positive Regulation Of Osteoclast Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process	Cell-substrate Junction Assembly Fibroblast Migration
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33339817 33547301) Chronic lymphocytic leukemia ( 23770605) IgA nephropathy ( 26028593) Liver enzyme levels (alanine transaminase) ( 33972514) Neurofibrillary tangles ( 31497858) Urate levels ( 31578528)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Asthma and hay fever ( 24388013) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease ( 33909500 30804561) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Coronary artery disease ( 33020668 29212778) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Diastolic blood pressure ( 27841878 28135244) Diverticular disease ( 30177863) FEV1 ( 30804560) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels in HIV infection ( 33109212) Height ( 20881960 28552196 25429064 25282103 21998595) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Intraocular pressure ( 30054594 29785010 29617998 29235454) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560 28166213) Lung function (FVC) ( 30804560 28166213) Lung function (low FEV1 vs high FEV1) ( 26423011) Mitral valve prolapse ( 26301497) Myocardial infarction ( 33532862) Pulmonary function ( 20010834) Pulmonary function (smoking interaction) ( 23284291) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		17 interacting genes: BOP1 CDK2 CDK6 CRIP2 FBXW7 KAT2B LENG1 PIGC RPL14 SF3B3 SIAH1 SIN3A SNHG29 SP1 TNS1 TULP3 ZNF512B	16 interacting genes: AR CAPN2 EGFR ERBB2 ERBB3 ERBB4 FRS3 GAB1 KIT KLF10 MET OSGEP PPP1CC PTK2 RNF10 YWHAZ
Entrez ID		7071	7145
HPRD ID		03527	02512
Ensembl ID		ENSG00000155090	ENSG00000079308
Uniprot IDs		Q13118	A0A2R8Y4T1 A1L0S7 B2RU35 B7Z6H8 E9PF55 E9PGF5 Q0VG54 Q0VG55 Q59G71 Q86VB0 Q9HBL0
PDB IDs		2EPA
Enriched GO Terms of Interacting Partners?		Cyclin Binding Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Rhythmic Process Regulation Of Cell Cycle G2/M Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Hydroperoxide Nucleolus SAGA Complex Nucleoplasm Histone Acetyltransferase Binding Mitotic Cell Cycle Phase Transition Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cell Cycle Positive Regulation Of Apoptotic Signaling Pathway Cell Cycle Phase Transition Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Cyclin-dependent Protein Kinase Holoenzyme Complex Cyclin D2-CDK6 Complex Positive Regulation Of Hydrogen Sulfide Biosynthetic Process Cellular Response To Wortmannin Ribosomal Large Subunit Biogenesis Cellular Response To Tert-butyl Hydroperoxide Response To Methylglyoxal Regulation Of DNA-templated Transcription Regulation Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Y Chromosome Positive Regulation Of Heterochromatin Formation Regulation Of RNA Biosynthetic Process Cyclin A1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex Negative Regulation Of Myeloid Leukocyte Differentiation FBXO Family Protein Binding Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Transcription Repressor Complex Response To Wortmannin Bronchus Morphogenesis Limb Development Negative Regulation Of RRNA Processing Negative Regulation Of Lipid Biosynthetic Process Histone H3K9 Acetyltransferase Activity Cleavage In ITS2 Between 5.8S RRNA And LSU-rRNA Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Positive Regulation Of Chromatin Organization Regulation Of RNA Metabolic Process Cyclin-dependent Protein Kinase Activity	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Protein Tyrosine Kinase Activity Epidermal Growth Factor Receptor Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Activity Regulation Of Developmental Process Basal Plasma Membrane ERBB2 Signaling Pathway Receptor Complex Protein Phosphatase Binding Negative Regulation Of Programmed Cell Death Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Programmed Cell Death Protein Kinase Activity Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Phosphate Metabolic Process Regulation Of Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Neuron Differentiation Regulation Of Multicellular Organismal Process Positive Regulation Of Developmental Process Kinase Activity Positive Regulation Of Epithelial Cell Proliferation ERBB3:ERBB2 Complex Regulation Of MAPK Cascade Animal Organ Development Positive Regulation Of Protein Phosphorylation Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Positive Regulation Of MAPK Cascade Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Positive Regulation Of Phosphorylation Positive Regulation Of Intracellular Signal Transduction Signal Transduction Positive Regulation Of Multicellular Organismal Process Negative Regulation Of Apoptotic Process Transferase Activity Regulation Of Phosphorus Metabolic Process Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Growth Factor Binding Cellular Response To Epidermal Growth Factor Stimulus Protein Phosphorylation Peptidyl-tyrosine Phosphorylation Response To Epidermal Growth Factor Regulation Of Apoptotic Process Regulation Of Epithelial Cell Proliferation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?