NIF3L1 and DCTD

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NIF3L1	DCTD
Description		NGG1 interacting factor 3 like 1	dCMP deaminase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	Cytoplasm Cytosol
	Molecular Function	Protein Binding Identical Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Catalytic Activity DCMP Deaminase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Identical Protein Binding Metal Ion Binding 5-hydroxymethyl-dUMP N-hydrolase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Neuron Differentiation Positive Regulation Of DNA-templated Transcription	Pyrimidine Nucleotide Metabolic Process DUMP Biosynthetic Process DTMP Biosynthetic Process Nucleotide Biosynthetic Process Nucleoside Salvage
Pathways			Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Triptolide cytotoxicity ( 26121980)	Diisocyanate-induced asthma ( 25918132) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Wegener's granulomatosis ( 23740775)
Interacting Genes		93 interacting genes: ALKBH4 AP5B1 APIP ARPIN BDKRB2 BEND7 C14orf119 CASP7 CCDC102B CCDC85B CDKN2B CDKN2C CDKN2D COIL COPS2 CUTC CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DTX2 DUSP23 DUSP29 DYNLT3 EIF4A3 EIF5A2 ENOX1 EPHB6 FLAD1 FXR2 GNMT GRB2 IP6K3 KCNIP1 KCTD17 KCTD7 KCTD9 KRT15 KXD1 LAMTOR3 LMO2 LMO3 MAGEA11 MAPRE2 MLXIPL NATD1 NEK6 NGB NME1 NME7 NOL3 NUDT14 NUDT21 ORC5 PAFAH1B3 PAICS PCBD1 PNMA1 POLR1C PPIH PRTFDC1 PTPA RABAC1 RAD54B RPIA S100A1 SAT1 SEPTIN1 SNF8 SPG21 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SULT2A1 SYT17 TCL1A THOC7 TIFA TRAF2 TRIM21 TRIM27 TRIP13 TSC22D4 TXN VIM YES1 YWHAQ ZBED1	14 interacting genes: CEP76 DYRK1A FGF12 FXR1 GORASP2 LNX1 MALSU1 NIF3L1 NUDT18 PICK1 PSMA1 SDCBP TXN2 UBE2I
Entrez ID		60491	1635
HPRD ID		10424	09623
Ensembl ID		ENSG00000196290	ENSG00000129187
Uniprot IDs		Q9GZT8	P32321
PDB IDs			2W4L
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Cytoplasm Protein Binding Cytosol Protein Complex Oligomerization Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Ethanol Catabolic Process Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Ethanol Metabolic Process Nucleoside Phosphate Metabolic Process Phosphate-containing Compound Metabolic Process Sulfation Pyrimidine Nucleotide Metabolic Process Polyamine Catabolic Process Nucleus Ribose Phosphate Metabolic Process Reciprocal Meiotic Recombination
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