NIF3L1 and RAD54B

Number of citations of the paper that reports this interaction (PubMedID 19060904)
32

Data Source:
BioGRID (two hybrid)

		NIF3L1	RAD54B
Description		NGG1 interacting factor 3 like 1	RAD54 homolog B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	Nucleus
	Molecular Function	Protein Binding Identical Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Nucleotide Binding DNA Binding DNA Helicase Activity RNA Helicase Activity Helicase Activity Protein Binding ATP Binding DNA Translocase Activity Hydrolase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Neuron Differentiation Positive Regulation Of DNA-templated Transcription	Double-strand Break Repair Via Homologous Recombination DNA Repair Mitotic Recombination DNA Damage Response Reciprocal Meiotic Recombination Determination Of Adult Lifespan Response To Xenobiotic Stimulus Response To Ionizing Radiation
Pathways
Drugs
Diseases
GWAS		Triptolide cytotoxicity ( 26121980)	Age at first sexual intercourse ( 34211149) Nonsyndromic cleft lip with cleft palate ( 28232668)
Interacting Genes		93 interacting genes: ALKBH4 AP5B1 APIP ARPIN BDKRB2 BEND7 C14orf119 CASP7 CCDC102B CCDC85B CDKN2B CDKN2C CDKN2D COIL COPS2 CUTC CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DTX2 DUSP23 DUSP29 DYNLT3 EIF4A3 EIF5A2 ENOX1 EPHB6 FLAD1 FXR2 GNMT GRB2 IP6K3 KCNIP1 KCTD17 KCTD7 KCTD9 KRT15 KXD1 LAMTOR3 LMO2 LMO3 MAGEA11 MAPRE2 MLXIPL NATD1 NEK6 NGB NME1 NME7 NOL3 NUDT14 NUDT21 ORC5 PAFAH1B3 PAICS PCBD1 PNMA1 POLR1C PPIH PRTFDC1 PTPA RABAC1 RAD54B RPIA S100A1 SAT1 SEPTIN1 SNF8 SPG21 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SULT2A1 SYT17 TCL1A THOC7 TIFA TRAF2 TRIM21 TRIM27 TRIP13 TSC22D4 TXN VIM YES1 YWHAQ ZBED1	30 interacting genes: ANKRD36BP1 ATPAF2 BAAT CCDC33 CDC23 CSNK1E DMC1 DYRK2 ELOA ENKD1 GMCL1 GORASP2 IGFBP3 LNX1 MDM4 MYO15B NIF3L1 NUDT18 PRKAA1 PSMA1 RAD51 RIBC2 SFRP2 SUMO1 TCEANC TRAPPC6A TRMO UBE2I WRN ZNF580
Entrez ID		60491	25788
HPRD ID		10424	05049
Ensembl ID		ENSG00000196290	ENSG00000197275
Uniprot IDs		Q9GZT8	Q9Y620
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Cytoplasm Protein Binding Cytosol Protein Complex Oligomerization Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Ethanol Catabolic Process Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Ethanol Metabolic Process Nucleoside Phosphate Metabolic Process Phosphate-containing Compound Metabolic Process Sulfation Pyrimidine Nucleotide Metabolic Process Polyamine Catabolic Process Nucleus Ribose Phosphate Metabolic Process Reciprocal Meiotic Recombination	DNA Strand Exchange Activity DNA Strand Invasion DNA Recombinase Assembly Small Protein Activating Enzyme Binding Catalytic Activity, Acting On DNA Response To Ionizing Radiation Response To Gamma Radiation Double-strand Break Repair Involved In Meiotic Recombination Cellular Response To Stress Lateral Element Cellular Response To Ionizing Radiation DNA Damage Response ATP-dependent DNA Damage Sensor Activity
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