NIF3L1 and NUDT14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NIF3L1	NUDT14
Description		NGG1 interacting factor 3 like 1	nudix hydrolase 14
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	Cytoplasm Cytosol
	Molecular Function	Protein Binding Identical Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Protein Binding UDP-sugar Diphosphatase Activity Hydrolase Activity Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides Identical Protein Binding Metal Ion Binding ADP-ribose Diphosphatase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Neuron Differentiation Positive Regulation Of DNA-templated Transcription	Nucleoside Phosphate Metabolic Process Protein N-linked Glycosylation Via Asparagine Ribose Phosphate Metabolic Process
Pathways			Synthesis of dolichyl-phosphate-glucose
Drugs
Diseases
GWAS		Triptolide cytotoxicity ( 26121980)	Brain morphology (MOSTest) ( 32665545) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Neutrophil count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		93 interacting genes: ALKBH4 AP5B1 APIP ARPIN BDKRB2 BEND7 C14orf119 CASP7 CCDC102B CCDC85B CDKN2B CDKN2C CDKN2D COIL COPS2 CUTC CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DTX2 DUSP23 DUSP29 DYNLT3 EIF4A3 EIF5A2 ENOX1 EPHB6 FLAD1 FXR2 GNMT GRB2 IP6K3 KCNIP1 KCTD17 KCTD7 KCTD9 KRT15 KXD1 LAMTOR3 LMO2 LMO3 MAGEA11 MAPRE2 MLXIPL NATD1 NEK6 NGB NME1 NME7 NOL3 NUDT14 NUDT21 ORC5 PAFAH1B3 PAICS PCBD1 PNMA1 POLR1C PPIH PRTFDC1 PTPA RABAC1 RAD54B RPIA S100A1 SAT1 SEPTIN1 SNF8 SPG21 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SULT2A1 SYT17 TCL1A THOC7 TIFA TRAF2 TRIM21 TRIM27 TRIP13 TSC22D4 TXN VIM YES1 YWHAQ ZBED1	11 interacting genes: ARAF LNX1 LNX2 NIF3L1 NTAQ1 RAF1 REL TEPSIN TERF1 TERF2IP ZCCHC10
Entrez ID		60491	256281
HPRD ID		10424	14847
Ensembl ID		ENSG00000196290	ENSG00000183828
Uniprot IDs		Q9GZT8	B3KXY7 O95848
PDB IDs			3Q91 8OTV
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Cytoplasm Protein Binding Cytosol Protein Complex Oligomerization Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Ethanol Catabolic Process Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Ethanol Metabolic Process Nucleoside Phosphate Metabolic Process Phosphate-containing Compound Metabolic Process Sulfation Pyrimidine Nucleotide Metabolic Process Polyamine Catabolic Process Nucleus Ribose Phosphate Metabolic Process Reciprocal Meiotic Recombination	Nuclear Telomere Cap Complex Shelterin Complex G-rich Strand Telomeric DNA Binding Telomere Capping MAP Kinase Kinase Kinase Activity Positive Regulation Of Peptidyl-serine Phosphorylation Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Regulation Of Peptidyl-serine Phosphorylation Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Protein-N-terminal Glutamine Amidohydrolase Activity Coated Vesicle Membrane Death-inducing Signaling Complex Assembly Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of DNA Recombination At Telomere Protein-N-terminal Asparagine Amidohydrolase Activity PDZ Domain Binding DNA Biosynthetic Process Regulation Of Protein Phosphorylation Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Phosphorylation Regulation Of Telomere Maintenance NF-kappaB Complex Telomere Organization Adenylate Cyclase Activator Activity Identical Protein Binding Negative Regulation Of DNA Metabolic Process Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Activity Ankyrin Repeat Binding Protection From Non-homologous End Joining At Telomere Zinc Ion Binding Regulation Of Phosphorus Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Telomere Localization Meiotic Telomere Clustering Telomeric D-loop Disassembly
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