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NIF3L1 and CDKN2C
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
NIF3L1
CDKN2C
Gene Name
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Mitochondrion
Nucleus
Cytoplasm
Cytosol
Molecular Function
GTP Cyclohydrolase I Activity
Protein Binding
GTP Binding
Transcription Factor Binding
Metal Ion Binding
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Protein Binding
Protein Kinase Binding
Biological Process
7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Cell Cycle Arrest
Negative Regulation Of Cell Proliferation
Negative Regulation Of Cell Growth
Negative Regulation Of Phosphorylation
Oligodendrocyte Differentiation
Negative Regulation Of Protein Serine/threonine Kinase Activity
Pathways
Cyclin D associated events in G1
Oxidative Stress Induced Senescence
G1 Phase
Cellular Senescence
Senescence-Associated Secretory Phenotype (SASP)
Oncogene Induced Senescence
Mitotic G1-G1/S phases
Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Ventricular conduction (
21076409
)
Protein-Protein Interactions
64 interactors:
AP5B1
APIP
ARPIN
BEND7
CCDC102B
CCDC85B
CDKN2B
CDKN2C
COIL
COPS2
CUTC
DCDC2
DCTD
DCTPP1
DHPS
DMC1
DMRTB1
DUSP23
DYNLT3
EIF5A2
ENOX1
EPHB6
FAM49B
FXR2
GNMT
GRB2
KCTD17
KRT15
KXD1
LAMTOR3
LMO2
MAGEA11
MAPRE2
MLXIPL
NATD1
NME1
NOL3
NUDT14
NUDT21
ORC5
PAICS
PCBD1
PRTFDC1
RABAC1
RAD54B
RPIA
S100A1
SAT1
SNF8
STAT3
STK16
SULT1A2
SULT1A3
SYT17
THOC7
TIFA
TRAF2
TRIM21
TRIP13
TSC22D4
VIM
YES1
YWHAQ
ZBED1
27 interactors:
AHCYL1
APLP1
ATM
ATR
CCDC90B
CDK4
CDK6
CDKN2A
COPS6
DRAP1
GDF9
GOPC
LRIF1
LY96
MAPK10
MAPK8
NAGK
NHP2L1
NIF3L1
PPP2CA
RBM48
REL
TCF12
TCF4
TLE1
TP53
UNC119
Entrez ID
60491
1031
HPRD ID
10424
04534
Ensembl ID
ENSG00000196290
ENSG00000123080
Uniprot IDs
Q9GZT8
P42773
Q6ICV4
PDB IDs
1BU9
1G3N
1IHB
1MX2
1MX4
1MX6
Enriched GO Terms of Interacting Partners
?
Protein Oligomerization
Nucleobase-containing Compound Metabolic Process
Protein Tetramerization
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Nitrogen Compound Metabolic Process
Nucleoside Metabolic Process
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Protein Complex Assembly
Protein Homotetramerization
Purine Nucleoside Metabolic Process
Protein Homooligomerization
Peptidyl-lysine Modification To Peptidyl-hypusine
Polyamine Metabolic Process
Polyamine Catabolic Process
Ribose Phosphate Metabolic Process
Reciprocal Meiotic Recombination
Nucleotide Metabolic Process
Amine Metabolic Process
Ribonucleotide Metabolic Process
Biosynthetic Process
Cellular Metabolic Process
Purine Nucleotide Metabolic Process
S-adenosylmethionine Metabolic Process
Methionine Metabolic Process
Regulation Of Protein Homodimerization Activity
Cellular Component Assembly
Sulfation
Sulfur Compound Metabolic Process
Positive Regulation Of T Cell Activation
Gene Expression
Amine Biosynthetic Process
Oocyte Maturation
Positive Regulation Of Homotypic Cell-cell Adhesion
Transcription, DNA-templated
Regulation Of Glycolytic Process
Meiosis I
Organophosphate Metabolic Process
Male Meiosis I
Cell Cycle Process
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Cell-cell Adhesion
RNA Biosynthetic Process
Response To Injury Involved In Regulation Of Muscle Adaptation
Deoxyhypusine Biosynthetic Process From Spermidine
Glucose Mediated Signaling Pathway
Polyamine Homeostasis
Response To Brefeldin A
Replicative Senescence
Regulation Of Gene Expression
Regulation Of Protein Metabolic Process
Regulation Of Metabolic Process
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Signal Transduction
Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Cell Cycle Arrest
Regulation Of Nitrogen Compound Metabolic Process
Cell Cycle Process
Cell Aging
Positive Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Metabolic Process
Positive Regulation Of Gene Expression
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Cell Cycle Arrest
Mitotic Cell Cycle Process
RNA Metabolic Process
Cell Cycle
Negative Regulation Of Growth
Regulation Of Intracellular Signal Transduction
Response To Radiation
Negative Regulation Of Cell Cycle
Regulation Of Signal Transduction
Signal Transduction
Mitotic Cell Cycle
JUN Phosphorylation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Cell Death
Positive Regulation Of Cell Aging
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Signaling
Negative Regulation Of Cell Growth
Response To Gamma Radiation
Regulation Of Signaling
Positive Regulation Of Cellular Metabolic Process
Response To Light Stimulus
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Apoptotic Process
Cell Communication
Positive Regulation Of Programmed Cell Death
Cellular Metabolic Process
Cellular Response To Ionizing Radiation
Positive Regulation Of Cell Death
Tagcloud
?
a134c
abp
allelic
ankyrin
balb
cdk6
cdnas
chr
congenic
d2
dba
g232a
ifna
inbred
inefficient
ink4c
le
multigenic
mus
p15
p16
p18
pctr1
plasmacytoma
pristane
spretus
typed
Tagcloud (Difference)
?
a134c
abp
allelic
ankyrin
balb
cdk6
cdnas
chr
congenic
d2
dba
g232a
ifna
inbred
inefficient
ink4c
le
multigenic
mus
p15
p16
p18
pctr1
plasmacytoma
pristane
spretus
typed
Tagcloud (Intersection)
?