NIF3L1 and FXR2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NIF3L1	FXR2
Gene Name		NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)	fragile X mental retardation, autosomal homolog 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion	Nucleus Cytoplasm Polysome Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	GTP Cyclohydrolase I Activity Protein Binding GTP Binding Transcription Factor Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Translation
Pathways
Drugs
Diseases
GWAS			IgM levels ( 23118916) Sex hormone-binding globulin levels ( 22675492)
Protein-Protein Interactions		64 interactors: AP5B1 APIP ARPIN BEND7 CCDC102B CCDC85B CDKN2B CDKN2C COIL COPS2 CUTC DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DUSP23 DYNLT3 EIF5A2 ENOX1 EPHB6 FAM49B FXR2 GNMT GRB2 KCTD17 KRT15 KXD1 LAMTOR3 LMO2 MAGEA11 MAPRE2 MLXIPL NATD1 NME1 NOL3 NUDT14 NUDT21 ORC5 PAICS PCBD1 PRTFDC1 RABAC1 RAD54B RPIA S100A1 SAT1 SNF8 STAT3 STK16 SULT1A2 SULT1A3 SYT17 THOC7 TIFA TRAF2 TRIM21 TRIP13 TSC22D4 VIM YES1 YWHAQ ZBED1	90 interactors: AMOTL2 AP1M1 AP2M1 ARL6IP1 BAZ2B BRCA1 BYSL C10orf62 C1orf35 CALCOCO2 CAMK2D CBS CCDC33 CCDC85B CDKL3 CEP44 CEP55 COIL CYFIP1 CYFIP2 DPPA2 EWSR1 FAM90A1 FBP1 FMR1 FTH1 FXR1 GKAP1 HMBOX1 HNRNPC KCNRG KCTD4 KIAA1217 KIF1A KRT20 KXD1 LASP1 LCMT1 LCP2 LDOC1 MBIP MCRS1 MEAF6 MFAP1 MIA3 MORF4L1 MRPL43 NCK2 NDN NECAB2 NIF3L1 NME1 NONO NT5C2 PAF1 PAICS PCBD1 PIM1 POM121 PRAM1 PSME3 PTS RABAC1 RALYL RBBP8 RBMX RBPMS RPIA RTN3 RTN4 SCEL SNAP23 SRPK2 SSSCA1 SYT6 SYTL4 TBC1D22B THAP1 TNNT1 TRAF2 TRIM23 TRIM29 TRIM37 TSC22D4 YES1 ZBTB22 ZBTB8A ZMAT2 ZNF451 ZSCAN1
Entrez ID		60491	9513
HPRD ID		10424	05629
Ensembl ID		ENSG00000196290	ENSG00000129245
Uniprot IDs		Q9GZT8	P51116
PDB IDs			3H8Z
Enriched GO Terms of Interacting Partners?		Protein Oligomerization Nucleobase-containing Compound Metabolic Process Protein Tetramerization Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Nitrogen Compound Metabolic Process Nucleoside Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Protein Complex Assembly Protein Homotetramerization Purine Nucleoside Metabolic Process Protein Homooligomerization Peptidyl-lysine Modification To Peptidyl-hypusine Polyamine Metabolic Process Polyamine Catabolic Process Ribose Phosphate Metabolic Process Reciprocal Meiotic Recombination Nucleotide Metabolic Process Amine Metabolic Process Ribonucleotide Metabolic Process Biosynthetic Process Cellular Metabolic Process Purine Nucleotide Metabolic Process S-adenosylmethionine Metabolic Process Methionine Metabolic Process Regulation Of Protein Homodimerization Activity Cellular Component Assembly Sulfation Sulfur Compound Metabolic Process Positive Regulation Of T Cell Activation Gene Expression Amine Biosynthetic Process Oocyte Maturation Positive Regulation Of Homotypic Cell-cell Adhesion Transcription, DNA-templated Regulation Of Glycolytic Process Meiosis I Organophosphate Metabolic Process Male Meiosis I Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cell-cell Adhesion RNA Biosynthetic Process Response To Injury Involved In Regulation Of Muscle Adaptation Deoxyhypusine Biosynthetic Process From Spermidine Glucose Mediated Signaling Pathway Polyamine Homeostasis Response To Brefeldin A	RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cellular Process Cellular Process Negative Regulation Of Centriole Replication Macromolecule Biosynthetic Process Developmental Cell Growth Protein Homooligomerization Tetrahydrobiopterin Biosynthetic Process Pteridine-containing Compound Biosynthetic Process Endoplasmic Reticulum Tubular Network Organization Cellular Macromolecule Biosynthetic Process Protein Autoubiquitination Protein Oligomerization Histone Acetylation Vesicle-mediated Transport Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Regulation Of Centriole Replication Histone H4 Acetylation Internal Protein Amino Acid Acetylation Pteridine-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Negative Regulation Of Gene Expression Protein Acetylation DNA Recombination Histone H2A Acetylation Cellular Metabolic Process Neuron Projection Extension Negative Regulation Of Centrosome Duplication Cell Growth Negative Regulation Of Cell Growth Histone Modification
Tagcloud ?			17p13 adipocytes array cgh disability duplication dysmorphic encodes encompassing facial fingers fissures glut4 hyperpigmentation intellectual mandible nlgn2 nostrils obesity p13 palpebral proposita recognizable referred seizures slc2a4 slender tp53 upturned
Tagcloud (Difference) ?			17p13 adipocytes array cgh disability duplication dysmorphic encodes encompassing facial fingers fissures glut4 hyperpigmentation intellectual mandible nlgn2 nostrils obesity p13 palpebral proposita recognizable referred seizures slc2a4 slender tp53 upturned
Tagcloud (Intersection) ?