SNRPC and WWP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SNRPC	WWP2
Gene Name		small nuclear ribonucleoprotein polypeptide C	WW domain containing E3 ubiquitin protein ligase 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Commitment Complex Nucleoplasm U1 SnRNP Cajal Body U2-type Prespliceosome	Ubiquitin Ligase Complex Nucleus Cytoplasm Membrane Extracellular Vesicular Exosome
	Molecular Function	Single-stranded RNA Binding MRNA Binding Protein Binding Zinc Ion Binding U1 SnRNA Binding Protein Homodimerization Activity Poly(A) RNA Binding	RNA Polymerase II Transcription Factor Binding Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Ligase Activity
	Biological Process	Spliceosomal SnRNP Assembly MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome	Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Protein Modification Process Negative Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Transporter Activity Regulation Of Ion Transmembrane Transport Regulation Of Membrane Potential Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell Negative Regulation Of Protein Transport Protein Autoubiquitination Protein K63-linked Ubiquitination Regulation Of Potassium Ion Transmembrane Transporter Activity
Pathways
Drugs
Diseases
GWAS			IgE levels ( 23146381)
Protein-Protein Interactions		28 interactors: AES AGGF1 DDX42 EWSR1 EXOSC8 FAM168A GOLGA2 HNRNPD HNRNPF HNRNPH2 HNRNPUL1 HSD17B14 ILF3 KHDRBS3 MAGED1 NCAPH2 PSMA3 RBFOX2 RBM11 RBM4 RBPMS RFX6 RNF31 SNRNP70 SPAG8 SS18L1 WDR77 WWP2	53 interactors: ANKRD44 ARRDC1 ATN1 CDC34 CLCN5 CPSF6 DAG1 DIDO1 EGR2 EWSR1 FAM189A2 FBXL18 HNRNPUL1 IL2RG IL6R LGALS9B NDFIP2 PAIP1 PDLIM7 POLR2A POU5F1 RASA1 RNF11 RUSC1 SCAMP3 SCN5A SCNN1A SCNN1B SCNN1G SF1 SFTPC SMAD3 SMAD7 SNRPC SPG20 TFAP2A TNK2 TP53BP2 TRAF4 UBC UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2J2 UBE2K UBE2L3 USP7 VASP VPS37C WBP1 WBP2 WIPF1
Entrez ID		6631	11060
HPRD ID		04630	03812
Ensembl ID			ENSG00000198373
Uniprot IDs		P09234 Q5TAL4	B4DHF6 O00308
PDB IDs		2VRD 3CW1
Enriched GO Terms of Interacting Partners?		RNA Processing Gene Expression RNA Splicing MRNA Metabolic Process RNA Metabolic Process MRNA Processing Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Circadian Regulation Of Translation Cellular Metabolic Process Regulation Of Circadian Rhythm Metabolic Process Regulation Of Protein Binding Transcription, DNA-templated RNA Biosynthetic Process Protein Polyubiquitination Circadian Rhythm Positive Regulation Of Gene Expression Pancreatic D Cell Differentiation Pancreatic Epsilon Cell Differentiation Positive Regulation Of Cellular Metabolic Process Glandular Epithelial Cell Differentiation Negative Regulation Of Protein Binding CD40 Signaling Pathway Regulation Of Cellular Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Binding Negative Regulation Of Biosynthetic Process Regulation Of Translation Protein Linear Polyubiquitination Cellular Macromolecule Biosynthetic Process Negative Regulation Of Translation Regulation Of Epithelial Cell Proliferation	Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteasomal Protein Catabolic Process Transcription Initiation From RNA Polymerase II Promoter Excretion Response To Organic Substance DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Ubiquitination Positive Regulation Of Cellular Protein Metabolic Process Protein K11-linked Ubiquitination Sodium Ion Homeostasis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Gene Expression Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Transcription, DNA-templated Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Stimulus Positive Regulation Of Ossification Regulation Of Ossification RNA Biosynthetic Process Regulation Of Protein Ubiquitination Apoptotic Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Regulation Of Cellular Protein Metabolic Process Viral Process Apoptotic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Protein Catabolic Process RNA Processing Multicellular Organismal Water Homeostasis Programmed Cell Death Negative Regulation Of Transcription By Competitive Promoter Binding Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Proteolysis Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?			accelerating anticancer biomarker cascade catalyzes contributes counterparts deleted dramatic e3 encodes final homologue ligase ligases malignancies member nedd4 neoplastic oscc osccs pi3k promotion pten ten tensin tumoral ubiquitination
Tagcloud (Difference) ?			accelerating anticancer biomarker cascade catalyzes contributes counterparts deleted dramatic e3 encodes final homologue ligase ligases malignancies member nedd4 neoplastic oscc osccs pi3k promotion pten ten tensin tumoral ubiquitination
Tagcloud (Intersection) ?