SNRPC and WDR77

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		SNRPC	WDR77
Gene Name		small nuclear ribonucleoprotein polypeptide C	WD repeat domain 77
Image
Gene Ontology Annotations	Cellular Component	Commitment Complex Nucleoplasm U1 SnRNP Cajal Body U2-type Prespliceosome	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome
	Molecular Function	Single-stranded RNA Binding MRNA Binding Protein Binding Zinc Ion Binding U1 SnRNA Binding Protein Homodimerization Activity Poly(A) RNA Binding	Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Spliceosomal SnRNP Assembly MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome	Spliceosomal SnRNP Assembly Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Gene Expression NcRNA Metabolic Process Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Pathways			Chromatin modifying enzymes snRNP Assembly Chromatin organization Metabolism of non-coding RNA RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: AES AGGF1 DDX42 EWSR1 EXOSC8 FAM168A GOLGA2 HNRNPD HNRNPF HNRNPH2 HNRNPUL1 HSD17B14 ILF3 KHDRBS3 MAGED1 NCAPH2 PSMA3 RBFOX2 RBM11 RBM4 RBPMS RFX6 RNF31 SNRNP70 SPAG8 SS18L1 WDR77 WWP2	35 interactors: AQR BAG2 COPRS CTDP1 GPKOW HIST2H2AB HNRNPM LSM3 NKX3-1 PCBP2 PPIL1 PPP1R8 PQBP1 PRMT5 QKI RBM5 SAP30BP SF1 SF3A1 SF3B4 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZNF207
Entrez ID		6631	79084
HPRD ID		04630	14387
Ensembl ID			ENSG00000116455
Uniprot IDs		P09234 Q5TAL4	B4DP38 Q9BQA1
PDB IDs		2VRD 3CW1	4GQB
Enriched GO Terms of Interacting Partners?		RNA Processing Gene Expression RNA Splicing MRNA Metabolic Process RNA Metabolic Process MRNA Processing Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Circadian Regulation Of Translation Cellular Metabolic Process Regulation Of Circadian Rhythm Metabolic Process Regulation Of Protein Binding Transcription, DNA-templated RNA Biosynthetic Process Protein Polyubiquitination Circadian Rhythm Positive Regulation Of Gene Expression Pancreatic D Cell Differentiation Pancreatic Epsilon Cell Differentiation Positive Regulation Of Cellular Metabolic Process Glandular Epithelial Cell Differentiation Negative Regulation Of Protein Binding CD40 Signaling Pathway Regulation Of Cellular Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Binding Negative Regulation Of Biosynthetic Process Regulation Of Translation Protein Linear Polyubiquitination Cellular Macromolecule Biosynthetic Process Negative Regulation Of Translation Regulation Of Epithelial Cell Proliferation	RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing MRNA Metabolic Process Gene Expression RNA Metabolic Process Ribonucleoprotein Complex Assembly Spliceosomal SnRNP Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Transcription, DNA-templated Histone MRNA Metabolic Process RNA Biosynthetic Process Cellular Metabolic Process Cellular Component Assembly NcRNA Metabolic Process Termination Of RNA Polymerase II Transcription DNA-templated Transcription, Termination MRNA 3'-end Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA 3'-end Processing MRNA 3'-splice Site Recognition Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Histone Methylation Regulation Of RNA Metabolic Process MRNA Splice Site Selection Biosynthetic Process Histone H4-R3 Methylation Protein Methylation Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Alternative MRNA Splicing, Via Spliceosome Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of RNA Splicing Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription
Tagcloud ?			androgen androgens ar ara70 ara70alpha ara70beta art benign coactivator coactivators corepressor cytoplasmic dysregulation ele1 exhibiting inhibitions internally luciferase mep50 ncoa4 p44 pca promotion spliced suppressive switch switches tblr1 versions
Tagcloud (Difference) ?			androgen androgens ar ara70 ara70alpha ara70beta art benign coactivator coactivators corepressor cytoplasmic dysregulation ele1 exhibiting inhibitions internally luciferase mep50 ncoa4 p44 pca promotion spliced suppressive switch switches tblr1 versions
Tagcloud (Intersection) ?