SNRPC and DDX42

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		SNRPC	DDX42
Gene Name		small nuclear ribonucleoprotein polypeptide C	DEAD (Asp-Glu-Ala-Asp) box helicase 42
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Commitment Complex Nucleoplasm U1 SnRNP Cajal Body U2-type Prespliceosome	Nucleus Nucleoplasm Cytoplasm Cajal Body Membrane Nuclear Speck
	Molecular Function	Single-stranded RNA Binding MRNA Binding Protein Binding Zinc Ion Binding U1 SnRNA Binding Protein Homodimerization Activity Poly(A) RNA Binding	Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome	Protein Localization Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: AES AGGF1 DDX42 EWSR1 EXOSC8 FAM168A GOLGA2 HNRNPD HNRNPF HNRNPH2 HNRNPUL1 HSD17B14 ILF3 KHDRBS3 MAGED1 NCAPH2 PSMA3 RBFOX2 RBM11 RBM4 RBPMS RFX6 RNF31 SNRNP70 SPAG8 SS18L1 WDR77 WWP2	10 interactors: APP DHX15 FBXO25 PRPF19 RECQL5 SF3A1 SF3B4 SNRPC U2SURP UBC
Entrez ID		6631	11325
HPRD ID		04630	09909
Ensembl ID			ENSG00000198231
Uniprot IDs		P09234 Q5TAL4	Q86XP3
PDB IDs		2VRD 3CW1
Enriched GO Terms of Interacting Partners?		RNA Processing Gene Expression RNA Splicing MRNA Metabolic Process RNA Metabolic Process MRNA Processing Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Circadian Regulation Of Translation Cellular Metabolic Process Regulation Of Circadian Rhythm Metabolic Process Regulation Of Protein Binding Transcription, DNA-templated RNA Biosynthetic Process Protein Polyubiquitination Circadian Rhythm Positive Regulation Of Gene Expression Pancreatic D Cell Differentiation Pancreatic Epsilon Cell Differentiation Positive Regulation Of Cellular Metabolic Process Glandular Epithelial Cell Differentiation Negative Regulation Of Protein Binding CD40 Signaling Pathway Regulation Of Cellular Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Binding Negative Regulation Of Biosynthetic Process Regulation Of Translation Protein Linear Polyubiquitination Cellular Macromolecule Biosynthetic Process Negative Regulation Of Translation Regulation Of Epithelial Cell Proliferation	RNA Processing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Splicing Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Regulation Of Cell Cycle Phase Transition Spliceosomal SnRNP Assembly Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway MRNA Splice Site Selection Cellular Metabolic Process Ribonucleoprotein Complex Biogenesis Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Generation Of Catalytic Spliceosome For First Transesterification Step Regulation Of ERBB Signaling Pathway Regulation Of MRNA Processing Signal Transduction In Response To DNA Damage Regulation Of RNA Splicing Synaptic Growth At Neuromuscular Junction Regulation Of Cell Cycle Process Collateral Sprouting In Absence Of Injury Protein Ubiquitination Notch Signaling Pathway MRNA 5'-splice Site Recognition DNA Repair Protein Modification By Small Protein Conjugation DNA Damage Checkpoint Cellular Macromolecular Complex Assembly Collateral Sprouting Axon Midline Choice Point Recognition MRNA 3'-splice Site Recognition Protein Polyubiquitination Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Gene Expression Axon Choice Point Recognition Negative Regulation Of Neuron Differentiation
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